Celiac disease is an autoimmune induced inflammatory disease of small intestine in genetically susceptible individuals by ingestion of gluten. Clinical manifestation of celiac disease is mostly gastrointestinal or atypical non-gastrointestinal symptoms or silent with no symptoms, despite the presence of a characteristic intestinal lesion. Wider spectrum of atypical symptoms include neurological...

Astrocytic hamartomas of the retina are the principal ocular manifestation of tuberous sclerosis complex. Iris abnormalities are rare in tuberous sclerosis complex and include focal areas of stromal depigmentation and atypical colobomata. We describe 2 patients who were found on histopathological examination to have lesions consistent with hamartomas of the iris pigment epithelium and ciliary b...

When a morph face is produced with equal physical contributions from a typical parent face and an atypical parent face, the morph is judged to be more similar to the atypical parent. This discontinuity between physical and perceptual distance relationships, called the "atypicality bias" (Tanaka et al 1998, Cognition 68 199-220), has also been demonstrated with non-face objects (birds and cars; ...

PURPOSE Understanding which pathogens are associated with clinical manifestation of community-acquired pneumonia (CAP) is important to optimise treatment. We performed a study on the aetiology of CAP and assessed possible implications for patient management in the Netherlands. METHODS Patients with CAP attending the emergency department of a general hospital were invited to participate in the...

Chikungunya fever is an important arthropod-borne viral disease. The re-emergence of Chikungunya fever in 2006 has drawn global attention due to its explosive onset, rapid spread, high morbidity and myriad clinical atypical manifestations. The aim of the present work was to look for atypical manifestations following CHIKV infection in southern districts of Tamilnadu during 2010 outbreak. In thi...

Abstract Rare genetic diseases are a major cause of severe illnesses and deaths in new-borns infants. Disease manifestation critically ill children may be atypical or incomplete, making monogenetic disease difficult to diagnose clinically. Rapid exome genome (“genomic”) sequencing demonstrated profound diagnostic clinical value, there is growing evidence that the faster molecular diagnosis esta...

Pregnant women are at an increased risk for severe COVID-19 illness. Apart from the typical clinical manifestations, atypical presenting features of also being found. We report case a 20 years old COVID positive antenatal patient with pancytopenia. The presented scar tenderness and was taken up emergency caesarean section platelet count 5860 per microlitre. She managed intraoperative postoperat...