Development of the human auditory brainstem is thought to be primarily complete by the age of approximately 2 years, such that subsequent sensory plasticity is confined primarily to the cortex. However, recent findings have revealed experience-dependent developmental plasticity in the mammalian auditory brainstem in an animal model. It is not known whether the human system demonstrates similar ...

Auditory brainstem response (ABR) reflects activation of the neural generators along the ascending auditory pathway when a sound is heard. In this study, we explored the relationship between brainstem encoding of click and speech signals in normal-learning children and in those with language-based learning problems. To that end, ABR was recorded from both types of stimuli. We found that the nor...

A child was referred for an audiologic evaluation, to include auditory brainstem evoked response testing, due to inconsistent responses to sound and delayed speech and language development. Results were characteristic of auditory neuropathy. In view of subsequent decline in motor function, a genetics evaluation was conducted, revealing a mitochondrial disorder. A brief overview of mitochondrial...

Speech is an ecologically essential signal, whose processing crucially involves the subcortical nuclei of the auditory brainstem, but there are few experimental options for studying these early responses in human listeners under natural conditions. While encoding of continuous natural speech has been successfully probed in the cortex with neurophysiological tools such as electroencephalography ...

INTRODUCTION AND OBJECTIVE Severe jaundice that requires exchange transfusion has become a relatively rare situation today. About 60% of full term neonates and 80% of premature ones will suffer from jaundice within the first week of life. Hyperbilirubinemia at birth is a risk factor associated with hearing loss that is usually further linked to other factors that might have an effect on hearing...

OBJECTIVES This study investigated whether neurophysiologic responses (auditory evoked potentials) differ between typically developed children and children with phonological disorders and whether these responses are modified in children with phonological disorders after speech therapy. METHODS The participants included 24 typically developing children (Control Group, mean age: eight years and...

Speech-evoked auditory brainstem responses (ABRs) and speech recognition measures were evaluated in children with unilateral hearing loss (UHL) and normal hearing (NH). There were significant differences between the two hearing groups for several components of the response in quiet and in noise. Children with UHL performed worse than children with NH on all speech recognition measures in quiet ...

Health technology Two universal newborn hearing screening programmes, one using automated auditory brainstem response (AABR) and the other transient evoked otoacoustic emissions (TEOAE), were examined. Detailed pass criteria were reported for both programmes. The main difference between the two screening approaches was that AABR was performed by neonatal nurses, while TEOAE was conducted by mas...

Auditory deviance detection has been associated with a human auditory-evoked potential (AEP), the mismatch negativity, generated in the auditory cortex 100-200 ms from sound change onset. Yet, single-unit recordings in animals suggest much earlier (∼20-40 ms), and anatomically lower (i.e., thalamus and midbrain) deviance detection. In humans, recordings of the scalp middle-latency AEPs have con...

OBJECTIVE To evaluate the prognostic value of short-latency median nerve somatosensory evoked potentials and brainstem auditory evoked potentials in outcome prediction for comatose cardiac arrest patients treated with hypothermia. DESIGN Prospective, randomized, controlled trial of mild hypothermia after out-of-hospital cardiac arrest; a substudy of the European Hypothermia After Cardiac Arre...