Hemophagocytic lymphohistiocytosis (HLH) is a rare disorder of the mononuclear phagocytic system, characterised by histiocyte and lymphocyte activation. It can be classified as primary secondary HLH. Primary HLH usually presents in childhood, associated with gene mutations. Secondary adulthood, due to an underlying infection, autoimmune disease or malignancy. We describe case acute hepatitis-A ...

congenital hepatic fibrosis (chf) is a developmental disorder of the biliary system, characterized by defective remodeling of the ductal plate. herein a family of three children, from consanguineous parents, with minor thalassemia is presented who suffered from congenital hepatic fibrosis (chf). prompt diagnosis and appropriate treatment are necessary to avoid further complications in the affec...

Type 1 autoimmune hepatitis revealed by a dysphonia related to cricoarytenoid arthritis Sir, Autoimmune hepatitis disease may be accompanied , or revealed by, extra-hepatic (particularly rheumatological) manifestations, in approximately 5% of patients. 1 These manifestations include arth-ralgia, symmetrical non-erosive, non-deforming poly-arthritis, commonly localized on large articulations (kn...

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CONTEXT Azathioprine induced pancreatitis usually runs a benign self limited course with rapid disappearance of signs and symptoms upon with drawl of the drug. Azathioprine is used in treating relapses in patients with autoimmune pancreatitis and maintenance of remission in autoimmune hepatitis. Acute pancreatitis complicated by symptomatic pseudocysts requiring drainage is not usually associat...

INTRODUCTION Autoimmune hepatitis is an inflammatory disease with multifactorial ethiopatogenesis, characterized by lympho-monocytic infiltration of liver, presence of serum autoantibodies (ANA, SMA, LKM-1) and high levels of immunoglobulins. Overlap syndromes are defined as the association of autoimmune hepatitis with cholestatic diseases such as primary biliary cirrhosis and primary sclerosin...

We encountered two patients with overlapping features of primary biliary cholangitis and autoimmune hepatitis within the same family. A 68-year-old woman presented at our hospital from a previous medical institution because of the diagnosis of primary biliary cholangitis. Her 49-year-old daughter was admitted with liver dysfunction 4 years later. When compared, these two related patients were f...

Parvovirus B19 infection is usually self-limiting in immunocompetent individuals. Twenty-five percent of infected individuals are
 completely asymptomatic during infection, with 50% them presenting flu-like symptoms and the remaining patients presenting
 erythema infectiosum, arthralgia, or arthritis. More rarely, transient aplastic crisis seen chronic haemolytic
 disorders. Chro...