INTRODUCTION The rat median nerve injury and repair model gets increasingly important for research on novel bioartificial nerve grafts. It allows follow-up evaluation of the recovery of the forepaw functional ability with several sensitive techniques. The reflex-based grasping test, the skilled forelimb reaching staircase test, as well as electrodiagnostic recordings have been described useful ...

BACKGROUND The survival of autologous fat graft tissue is dependent on various factors, such as vascularization and inflammation. OBJECTIVE This study aims to evaluate the possible beneficial effects of dimethylsulfoxide (DMSO) on fat graft volume and survival. METHODS Eighteen male Wistar albino rats were divided randomly into three groups. An autologous fat graft obtained from the inguina...

Neointima formation is the major reason for vein graft failure. However, the underlying mechanism is unclear. The aim of this study was to determine the role of miR-26a in the development of neointimal hyperplasia of autogenous vein grafts. Using autologous jugular vein grafts in the rat carotid artery as a model, we found that miR-26a was significantly downregulated in grafted veins as well as...

We evaluated the use of hydroxyapatite blocks as spacers in pelvic osteotomy. The hydroxyapatite blocks fused with autologous bone tissue within 10 months and were highly biocompatible even after 10 years. They prevent pelvic deformities and are as effective as autogenous bone grafts.

This study evaluated 1) the efficacy of packing autologous fat grafts around temporomandibular joint (TMJ) total joint prosthetic reconstructions to prevent fibrosis and heterotopic bone formation and 2) the effects on postsurgical joint mobility and jaw function. One hundred fifteen patients (5 males and 110 females) underwent TMJ reconstruction with total joint prostheses and simultaneous fat...

BACKGROUND The amount of postoperative maxillary relapse of two different bone graft materials after Le Fort I osteotomy were compared in this study. OBJECTIVES The aim of this study is to compare postoperative maxillary relapse rates using heterologous and autologous graft materials after Le Fort I osteotomy. MATERIAL AND METHODS A total of 80 patients who had developmental malocclusion we...

Background: Chiari malformation type I (CM-I) is treated surgically by suboccipital craniectomy with or without duraplasty. Duraplasty may be performed using a variety of dural grafts, including autologous pericranium, allografts, xenografts, and synthetic substitutes. Aim: To assess outcome CSF leakage incidence according to graft in CM-I patients. Methods: This study included twenty-eight pat...

BACKGROUND Accelerated atherosclerosis is the main cause of late aortocoronary vein graft failure. We aimed to develop a large animal model for the study of pathogenesis and treatment of vein graft atherosclerosis. METHODS An autologous reversed jugular vein graft was inserted end-to-end into the transected common carotid artery of ten hypercholesteroemic minipigs. The vein grafts were invest...