نتایج جستجو برای: autologous stem cell transplantation

تعداد نتایج: 1901562  

Journal: :avicenna journal of medical biotechnology 0

spermatogonia are the male germ line stem cells whose life long expansion is needed for permanent production of spermatozoa. the present study was designed to examine the effect of hcg treatment on germ cell proliferation following stem cell transplantation in mice. spermatogonial stem cells were isolated from neonatal mice testes and characterized by alkaline phosphatase, immunoreactivity and ...

Journal: :Arthritis Research 2000
Dirk W van Bekkum

Treatment of rats suffering from florid chronic progressive systemic arthritis or from chronic remitting/relapsing encephalomyelitis with autologous bone marrow transplantation (BMT) is highly effective. This finding was unexpected as the genotype of the bone marrow largely determines the susceptibility of both spontaneous and induced autoimmune diseases in rodents. The success of autologous st...

Journal: :Stem cells 1995
J L Harousseau M Attal M Divine G Marit V Leblond A M Stoppa J H Bourhis D Caillot M Boasson J F Abgrall

Eighteen French centers reported 133 autologous stem cell transplantations performed after first remission induction in multiple myeloma. The source of stem cell was marrow (81 cases), blood (51 cases) or marrow plus blood (1 case). The immediate outcome after transplantation was 49 (37%) complete remissions (CRs) (13 maintained, 36 achieved), 61 (46%) partial remissions, 17 failures and 5 toxi...

2007
Kyoko Ono Seiichi Yokoo Tatsuya Mimura Tomohiko Usui Kazunori Miyata Makoto Araie Satoru Yamagami Shiro Amano

PURPOSE To evaluate the feasibility of autologous transplantation in a rabbit model of conjunctival epithelial cells cultured on amniotic membrane for ocular surface reconstruction. METHODS Limbal stem cell deficiency was induced in the right eyes of 30 rabbits. This was done by performing a lamellar keratectomy of the entire cornea and a complete removal of the limbus and conjunctiva, extend...

Journal: :Cell stem cell 2015
Penelope J Hallett Michela Deleidi Arnar Astradsson Gaynor A Smith Oliver Cooper Teresia M Osborn Maria Sundberg Michele A Moore Eduardo Perez-Torres Anna-Liisa Brownell James M Schumacher Roger D Spealman Ole Isacson

Autologous transplantation of patient-specific induced pluripotent stem cell (iPSC)-derived neurons is a potential clinical approach for treatment of neurological disease. Preclinical demonstration of long-term efficacy, feasibility, and safety of iPSC-derived dopamine neurons in non-human primate models will be an important step in clinical development of cell therapy. Here, we analyzed cynomo...

2009
C. J. Hawkey E. Ricart L. Chalkley S. Danese M. Allez M. Simpson M. Clark M. Bortlik V. Komarek D. Duricova M. Lukas

s of the 4th Congress of ECCO the European Crohn’s and Colitis Organisation S33 P056 Autologous Stem Cell Transplantation For Crohn’s disease (ASTIC) trial: early report of toxicity and efficacy C.J. Hawkey1 *, E. Ricart2, L. Chalkley1, S. Danese3, M. Allez4, J.F. Colombel5, M. Simpson1, M. Clark1. 1University of Nottingham, Nottingham, United Kingdom, 2Hospital Clinic, Barcelona 08036, Spain, ...

Journal: :Biology of Blood and Marrow Transplantation 2002

Davood Mehrabani, Farnaz Ghobadi, Golnoush Mehrabani,

Recent findings in stem cell biology have opened a new window in regenerative medicine. The endometrium possesses mesenchymal stem cells (MSCs) called endometrial stem cells (EnSCs) having specific regenerative properties linked to adult stem cells. They contribute in tissue remodeling and engineering and were shown to have immuno-modulating effects. Many clinical trials were undertaken to asce...

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