Correspondence to Sakari Kauppinen: [email protected] Abbreviations used in this paper: HCV, hepatitis C virus; LNA, locked nucleic acid; miRNA, microRNA; PS, phosphorothioate ; UTR, untranslated region. The discovery of microRNAs: From worm genetics to human disease The first miRNA gene, lin-4, was discovered in Caenorhabditis elegans by Victor Ambros and Gary Ruvkun in 1993 (Fig. 1), and shown to...

Probabilistic Soft Logic has been proposed and used in several applications as an efficient way to deal with inconsistency, uncertainty and relational representation. In several applications, this approach has led to an adequate description of the corresponding human reasoning. In this paper, we provide a theoretical explanation for one of the semi-heuristic choices made in this approach: namel...

the aim of this study was to examine the relationship between coaching self-efficacy and iran premier league wrestlers' sport commitment. the research method was descriptive-correlation. the wrestlers from 8 teams (n=120) including all wrestlers in iran premier league (2012) completed demographic questionnaire, coaching self-efficacy scale (feltz et al., 1999), and sport commitment questio...

introduction:.color is the first quality attribute of food evaluated by consumers, and is therefore an important quality component of food which influences consumer’s choice and preferences (maguire, 1994). color measurement of food products has been used as an indirect measure of other quality attributes such as flavor and contents of pigments because it is simpler, faster and correlates well ...

Cancer is one of the most virulent, devastating and deadliest disease in the world and it represents the second leading cause of death worldwide (Jemal et al., 2008; Siegel et al., 2012), with approximately 14 million new cases and 8.2 million cancer related deaths in 2012 (Ferlay et al., 2015). Chemotherapy is one of the most effective treatments for metastatic cancers (Chang, 2010). Multidrug...

Lyme disease, caused by Borrelia burgdorferi and transmitted by ticks, was initially considered a recent, rare and regional occurrence. We now have evidence that very similar bacteria infected humans in Europe during the ice age (Keller et al., 2012). Evidence-based data are scarce therefore many aspects of the disease remain controversial (Auwaerter et al., 2011; Lee and Vielmeyer, 2011; Perro...

how to cite this article: babaknejad n, sayehmiri f, sayehmiri k, mohamadkhani a, bahrami s. the relationship between zinc levels and autism: systematic review and meta-analysis. iran j child neurol. autumn 2016; 10(4):1-9.   abstract objective autism is a complex behaviorally defined disorder. there is a relationship between zinc (zn) levels in autistic patients and development of pathogenesis...

INTRODUCTION Wetlands are ecologically as well as economically important systems due to their high productivity, their nutrient (re)cycling capacities, and their prominent contribution to global greenhouse gas emissions. Being on the transition between terrestrial and—aquatic ecosystems, wetlands are buffers for terrestrial run off thereby preventing eutrophication of inland as well as coastal ...