نتایج جستجو برای: b lymphocyte

تعداد نتایج: 941540  

Journal: :The Journal of clinical investigation 1975
A S Fauci

This study was undertaken to determine the proportions and in vitro immune capacities of lymphocyte populations in the bone marrows of normal humans. Relatively pure mononuclear cell suspensions were obtained from bone marrow aspirates by linear sucrose gradient centrifugations. Simultaneous peripheral blood and bone marrow specimens from each individual were assayed for lymphocyte surface mark...

2015
Anders Svenningsson Joakim Bergman Ann Dring Mattias Vågberg Richard Birgander Thomas Lindqvist Jonathan Gilthorpe Tommy Bergenheim

OBJECTIVE We are conducting an open-label phase 1b study on the efficacy of intrathecal (IT) administration of rituximab, provided via an Ommaya reservoir, for the treatment of progressive multiple sclerosis (PMS). The objective of this initial study was to monitor B lymphocytes in peripheral blood (PB) and CSF from the first 10 patients 1 year posttreatment. METHODS Dose titration was perfor...

Journal: :Revista Brasileira de Cancerologia 2023

The non-Hodgkin's lymphomas are a heterogeneous group of diseases. Cell marker studies over the past 10-15 years have demonstrated that majority adult B cell lymphocyte origin while minority T origin. They vary in their prognosis according to histologic and clinical features.

2013
Sabrina Kneissl Qi Zhou Michael Schwenkert François-Loic Cosset Els Verhoeyen Christian J. Buchholz

B lymphocytes are an important cell population of the immune system. However, until recently it was not possible to transduce resting B lymphocytes with retro- or lentiviral vectors, making them unsusceptible for genetic manipulations by these vectors. Lately, we demonstrated that lentiviral vectors pseudotyped with modified measles virus (MV) glycoproteins hemagglutinin, responsible for recept...

Journal: :Haematologica 2010
Peter Van Loo Thomas Tousseyn Vera Vanhentenrijk Daan Dierickx Agnieszka Malecka Isabelle Vanden Bempt Gregor Verhoef Jan Delabie Peter Marynen Patrick Matthys Chris De Wolf-Peeters

BACKGROUND Gene expression profiling has successfully identified the prognostic significance of the host response in lymphomas. The aggressive T-cell/histiocyte-rich large B-cell lymphoma and the indolent nodular lymphocyte-predominant Hodgkin's lymphoma are both characterized by a paucity of tumor cells embedded in an overwhelming background. The tumor cells of both lymphomas share several cha...

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