As part of a multicentre study of porcine surfactant administration in respiratory distress syndrome, 29 babies weighing 2000 g or less were studied in the neonatal intensive care unit of the Royal Maternity Hospital, Belfast. Fourteen babies of a mean gestational age of 28.1 weeks were randomly allocated to the treatment group (200 mg/kg phospholipid given intratracheally) and 15 babies of a m...

AIM Differentiating features were sought for respiratory distress after water birth versus air birth in term low-risk babies. Clinical and X-ray features were to be assessed to determine if the disease processes could be differentiated. METHODS Review of case records and X-rays over a 7-year period for all admitted babies with respiratory distress after water birth and a similar group of babi...

There is evidence that oxidative stress plays a role in the development of chronic lung disease (CLD), with immature lungs being particularly sensitive to the injurious effect of oxygen and mechanical ventilation. We analyzed total ascorbate, urate, and protein carbonyls in 102 bronchoalveolar lavage fluid samples from 38 babies (33 preterm, 24-36 wk gestation; 5 term, 37-39 wk gestation). Pret...

BACKGROUND Routine hospital statistics for England appear to overestimate use of children's wards and include numbers of well newborn babies staying with their mothers after delivery ("well babies"). AIM To review trends in use of children's wards excluding data on newborn babies. METHODS We reviewed routine, published, and age stratified data requested from the Department of Health to iden...

A prospective study of 6825 labours was undertaken to determine the relation between the Apgar scores of the babies at one minute and the cardiotocograph tracing in labour. The sensitivity of an abnormal tracing was 35.2% for babies who needed intermittent positive pressure ventilation and 20.0% for babies who did not but who had Apgar scores of less than 7. The sensitivity of an abnormal traci...

OBJECTIVE To report mortality in babies enrolled on a community-based programme, Care of Next Infant Plus (CONI PLUS), which primarily supports parents anxious because of previous sudden unexpected death in infancy (SUDI) in their extended family or following an apparent life threatening event (ALTE) in their baby. DESIGN Prospective observational study from 1996 to 2010 in the UK. RESULTS ...

OBJECTIVE To compare the karyotype of babies conceived through ICSI with that of naturally conceived babies. DESIGN Prospective controlled study. SETTING The Egyptian IVF-ET Center, Cairo, Egypt. PATIENT(S) Four hundred and thirty babies conceived through ICSI and 430 babies conceived naturally. INTERVENTION(S) ICSI and karyotyping. MAIN OUTCOME MEASURE(S) Abnormal karyotype. RESULT...