BACKGROUND Bacterial pneumonia is a leading cause of illness and death worldwide, but quantifying its burden is difficult due to insensitive diagnostics. Although World Health Organization (WHO) protocol standardizes pediatric chest radiograph (CXR) interpretation for epidemiologic studies of bacterial pneumonia, its validity in adults is unknown. METHODS Patients (age ≥ 15 years) admitted wi...

Symbiotic microbial communities may interact with infectious pathogens sharing a common host. The microbiome may limit pathogen infection or, conversely, an invading pathogen can disturb the microbiome. Documentation of such relationships during naturally occurring disease outbreaks is rare, and identifying causal links from field observations is difficult. This study documented the effects of ...

Bacterial diseases are an important cause of mortality and morbidity worldwide. The Improper uncontrolled use antibiotics contribute to the bacterial resistance antibiotics.
 It is well known that stop infections by killing or
 
 inhibiting their growth. Antibiotics interfering with critical functions for To overcome this, bacteria developed different mechanisms resist survive. T...

PURPOSE To assess whether non-chlamydial bacterial infection is associated with trachomatous scarring in adults. METHODS This was a case-control study of 360 cases with trachomatous scarring but without trichiasis, and 360 controls without scarring. All participants underwent clinical examination, and a swab was taken from the inferior conjunctival fornix. Samples were inoculated onto blood a...

May, J. R., Herrick, N. C., and Thompson, D. (1972). Archives of Disease in Childhood, 47, 908. Bacterial infection in cystic fibrosis. Tests for precipitins against Staph. aureus, H. influenzae, Ps. aeruginosa, Strep. pnewnoniae, and Kleb. pneumoniae were carried out on the serum of 195 patients with cystic fibrosis, whose ages ranged from 3 weeks to 31 years. Sputum was obtained for culture f...

The periodontal disease is conformed by a group of illnesses affecting the gums and dental support structures. They are caused by certain bacteria found in the bacterial plaque. These bacteria are essential to the onset of illness; however, there are predisposing factors in both the host and the microorganisms that will have an effect on the pathogenesis of the illness. Periodontopathogenic bac...

Helicobacter pylori is probably the commonest bacterial infection worldwide and is now accepted as the cause of gastritis, peptic ulcer, gastric carcinoma, and gastric lymphoma. In the last few years, besides the local gasteroduodenal tissue damage, an association between H.pylori and various extra-intestinal pathologies had been described. Recent studies have suggested that H.pylori infection ...

Infection with gram-negative and gram-positive bacteria remains a leading cause of death in patients with systemic lupus erythematosis (SLE), even in the absence of immunosuppressive therapy. To elucidate the mechanisms that underly the increased risk of infection observed in patients with systemic autoimmunity, we have investigated host defense against bacterial infection in a murine model of ...