Epstein-Barr virus nuclear antigen 2 (EBNA 2) activates transcription of specific genes and is essential for B-lymphocyte transformation. EBNA 2 has an acidic activation domain which interacts with general transcription factors TFIIB, TFIIH, and TAF40. We now show that EBNA 2 is specifically bound to a novel nuclear protein, p100, and that p100 can coactivate gene expression mediated by the EBN...

Introduction Epstein-Barr  virus  (EBV)  infection  can  present  with  a  variety  of  manifestation. Case Report  Here  we  present  a  case  of  a  7  year- old  immunocompetent  girl  who  came  with  acute  abdominal  pain ,  had  echocardiographic  evidence  of  myocardial  dysfunction  and  finally  was  diagnosed  as  a  case  of  serologically  proven  acute  EBV  infection. Conclusion...

how to cite this article: hashemian s, ashrafzadeh f, akhondian j, beiraghi toosi m. epstein-barr virus encephalitis: a case report. iran j child neurol. 2015 winter;9(1):107-110.     abstract many neurologic manifestations of epstein-barr virus (ebv) infection have been documented, including encephalitis, aseptic meningitis, transverse myelitis, and guillain-barre syndrome. these manifestation...

Evidence of lytic infection of Epstein-Barr virus (EBV) in EBV-positive gastric carcinoma.stedt K, et al. Diagnostic implications of human cytomegalovirus immediate early-1 and pp67 mRNA detection in whole-blood samples from liver transplant patients using nucleic acid sequence-based amplification. Development of reverse transcriptase PCR assays for detection of active human herpesvirus 6 infec...

CD4 antigen levels in sera from asymptomatic intravenous drug users and homosexuals and patients with lymphadenopathy, acquired immunodeficiency syndrome-related complex, or acquired immunodeficiency syndrome were quantitated. Like soluble CD8, CD4 antigen levels were elevated in human immunodeficiency virus-seronegative asymptomatic intravenous drug users and homosexuals, probably reflecting i...

background and aims: infectious mononucleosis (im)is the clinical manifestation of primary infection with epstein-barr virus (ebv). humans are the only known reservoir of ebv. regarding the problems in diagnosis of the disease, the purpose of this study was to assess enzyme-linked immunosorbent assay (elisa) and nested polymerase chain reaction (pcr) as a diagnostic tool for this disease. mater...