LA-related protein 1 (LARP-1) belongs to an RNA-binding protein family containing a LA motif. Here, we identify LARP-1 as a regulator of sex determination. In C. elegans hermaphrodites, a complex regulatory network regulates the switch from sperm to oocyte production. We find that simultaneous depletion of larp-1 and the Nanos homologue nos-3 results in germline masculinization. This phenotype ...

Aggregation-based multilevel preconditioningof non-conforming FEM elasticity problems – p. 1/19

This paper presents the use of a finite element method (FEM) to analyze shear lag effect due flexure beams with an arbitrary cross-section and homogeneous elastic material. Beams are constrained by most common types supports, such as fixed, pinned, roller. The transverse, concentrated, or distributed loads act on through center cross-section. presented FEM transforms 3D analysis phenomenon into...

The purpose of this paper is to present an adaptive FEM-BEM coupling method that is valid for both twoand three-dimensional elasto-plastic analyses. The method takes care of the evolution of the elastic and plastic regions. It eliminates the cumbersome of a trial and error process in the identification of the FEM and BEM sub-domains in the standard FEM-BEM coupling approaches. The method estima...

The modular hybrid linear stepper motor in discussion has improved performances due to its novel construction. This linear motor can be one of the best choices for industrial applications where fast and accurate linear motions under heavy loads are required. In this paper a coupled simulation program of this motor will be presented. The basic part of the model is built up in SIMULINK. The force...

BACKGROUND AND OBJECTIVES We seek to compare and contrast the mechanisms of blood photocoagulation under 532 and 1,064 nm laser irradiation in vitro in order to better understand the in vivo observations. We also seek to validate a finite element model (FEM) developed to study the thermodynamics of coagulation. STUDY DESIGN/MATERIALS AND METHODS We study the photocoagulation of whole blood in...

We consider geometric biomembranes governed by an L-gradient flow for bending energy subject to area and volume constraints (Helfrich model). We give a concise derivation of a novel vector formulation, based on shape differential calculus, and corresponding discretization via parametric FEM using quadratic isoparametric elements and a semi-implicit Euler method. We document the performance of t...

Tube Hydroforming (THF) is getting an increasing amount of attention in industry. THF has advantages such as weight reduction, high dimensional accuracy, and high rigidity. However, this forming process requires precise control of internal pressure and axial feeding. Additionally, in most cases prebending processes must be performed on the tubes before the hydroforming process can be carried ou...

A Rectangular Dielectric Resonator Antenna (RDRA) is theoretically analyzed using the Conventional Dielectric Waveguide Model (CDWM), numerically simulated using the High Frequency Structure Simulator (HFSS) based on the Finite Element Method (FEM) software package and experimentally investigated with the consideration of the fundamental mode TE 111. Antenna parameters under investigation inclu...

Caenorhabditis elegans and Caenorhabditis briggsae are both self-fertile hermaphroditic nematodes that evolved independently from male/female ancestors. In C. elegans, FEM-1, FEM-2, and FEM-3 specify male fates by promoting proteolysis of the male-repressing transcription factor, TRA-1. Phenotypes of tra-1 and fem mutants are consistent with this simple linear model in the soma, but not in the ...