نتایج جستجو برای: bcaa

تعداد نتایج: 596  

Journal: :The American journal of clinical nutrition 1988
J A Vazquez H S Paul S A Adibi

We studied the effect of intravenously infused carnitine (34 mumol.100 g-1.d-1) on protein and branched-chain amino acid (BCAA) metabolism in rats either starved for 3 d or parenterally fed for 7 d. Carnitine infusion did not significantly affect nitrogen balance, protein content of liver and muscle, plasma concentrations of BCAA and branched-chain keto acid, or leucine oxidation and incorporat...

Journal: :American journal of physiology. Endocrinology and metabolism 2001
E Blomstrand B Saltin

Branched-chain amino acids (BCAA) or a placebo was given to seven subjects during 1 h of ergometer cycle exercise and a 2-h recovery period. Intake of BCAA did not influence the rate of exchange of the aromatic amino acids, tyrosine and phenylalanine, in the legs during exercise or the increase in their concentration in muscle. The increase was approximately 30% in both conditions. On the other...

Journal: :The Journal of nutrition 2006
Layne E Norton Donald K Layman

High-performance physical activity and postexercise recovery lead to significant changes in amino acid and protein metabolism in skeletal muscle. Central to these changes is an increase in the metabolism of the BCAA leucine. During exercise, muscle protein synthesis decreases together with a net increase in protein degradation and stimulation of BCAA oxidation. The decrease in protein synthesis...

Journal: :Human molecular genetics 2011
Nicola Brunetti-Pierri Brendan Lanpher Ayelet Erez Elitsa A Ananieva Mohammad Islam Juan C Marini Qin Sun Chunli Yu Madhuri Hegde Jun Li R Max Wynn David T Chuang Susan Hutson Brendan Lee

Therapy with sodium phenylacetate/benzoate or sodium phenylbutyrate in urea cycle disorder patients has been associated with a selective reduction in branched-chain amino acids (BCAA) in spite of adequate dietary protein intake. Based on this clinical observation, we investigated the potential of phenylbutyrate treatment to lower BCAA and their corresponding α-keto acids (BCKA) in patients with...

2012
Masahito Shimizu Masaya Kubota Takuji Tanaka Hisataka Moriwaki

Obesity and its related metabolic abnormalities, including insulin resistance, alterations in the insulin-like growth factor-1 (IGF-1)/IGF-1 receptor (IGF-1R) axis, and the state of chronic inflammation, increase the risk of colorectal cancer (CRC) and hepatocellular carcinoma (HCC). However, these findings also indicate that the metabolic disorders caused by obesity might be effective targets ...

Journal: :The Journal of nutrition 2006
Andrea Tom K Sreekumaran Nair

BCAAs are not synthesized in the body in humans, but they are crucial in protein and neurotransmitter synthesis. The protein anabolic role of BCAAs seems to be mediated not only by their important role as a promoter of the translation process (and possibly acting at the transcription level) but also by inhibition of protein degradation. Leucine may play a critical role in these signaling pathwa...

Journal: :Molecular medicine reports 2009
Minoru Itou Takumi Kawaguchi Eitaro Taniguchi Yuichiro Oku Nobuyoshi Fukushima Eiji Ando Tetsuharu Oriishi Yuki Uchida Momoka Otsuka Suiko Tanaka Shoko Iwasaki Mari Torii Kiyomi Yoshida Yuko Adachi Mariko Suga Manami Yoshiyama Ryoko Ibi Yoshiko Akiyama Machiko Takakura Keiichi Mitsuyama Osamu Tsuruta Michio Sata

Liver cirrhosis is frequently accompanied by malnutrition and hypoalbuminemia, which in turn commonly induces ascites in patients with liver cirrhosis. Ascites leads to abdominal distention and appetite loss, resulting in a deteriorated quality of life (QOL). Administration of branched-chain amino acid (BCAA)-rich supplements reduces hepatic encephalopathy and malnutrition. In addition, BCAAs b...

2016
I-Fan Chen Huey-June Wu Chung-Yu Chen Kuei-Ming Chou Chen-Kang Chang

BACKGROUND The decline in cognitive performance has been shown after fatiguing exercise. Branched-chain amino acids (BCAA) have been suggested to alleviate exercise-induced central fatigue. Arginine and citrulline could remove the excess NH3 accumulation accompanied with BCAA supplementation by increasing nitric oxide biosynthesis and/or urea cycle. The purpose of this study is to investigate t...

Journal: :The Journal of nutrition 2001
M Faure F Glomot I Papet

The catabolism of branched-chain amino acid (BCAA) differs between sheep and monogastric animals. The transamination of BCAA seems to be affected by development of the sheep. We studied the developmental changes in the activity and expression of the BCAA aminotransferase (BCAT) isoenzymes in skeletal muscle of sheep. Five muscles were taken from fetus, newborn, preruminant and ruminant lambs. B...

Journal: :The Plant cell 2017
Anqi Xing Robert L Last

The branched-chain amino acids (BCAAs) Ile, Val, and Leu are essential nutrients that humans and other animals obtain from plants. However, total and relative amounts of plant BCAAs rarely match animal nutritional needs, and improvement requires a better understanding of the mechanistic basis for BCAA homeostasis. We present an in vivo regulatory model of BCAA homeostasis derived from analysis ...

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