This review elucidates the roles of capillary haemodynamics, nitric oxide (NO) and vascular endothelial growth factor (VEGF) in the remodelling of skeletal muscle microcirculation in response to increased (electrical stimulation) or decreased (chronic ischaemia) blood flow. During early stages of stimulation-induced angiogenesis, up-regulation of VEGF and its receptor VEGF receptor 2 is depende...

In this work, a numerical study of the gas-solids flow in a 3D gas-fluidized bed with an immersed horizontal cylinder is performed using the combined computational fluid dynamics (CFD) and discrete element method (DEM). In order to investigate the wall effect, a sensitivity study of bed thickness is performed first to obtain the critical bed thickness at which the bed can be regarded as 3D. The...

One of the most important factors in determining the depth of foundations in structures adjacent to the water flow is the scouring phenomenon; the scouring is a phenomenon caused by the interactions between water flow and erodible bed materials, which causes the removal of sediments where hydraulic structures are located, including bridge piers. Every year, a great number of bridges are damaged...

The effects of seagrass bed geometry on wave attenuation and suspended sediment transport were investigated using a modified Nearshore Community Model (NearCoM). The model was enhanced to account for cohesive sediment erosion and deposition, sediment transport, combined wave and current shear stresses, and seagrass effects on drag. Expressions for seagrass drag as a function of seagrass shoot d...

It is known that marine sediments can support both compressional and shear waves. However, published work on scattering from irregular elastic media has not examined the influence of shear on sea bed scattering in detail. A perturbation model previously developed by the authors for joint roughness-volume scattering is used to study the effects of elasticity for three sea bed types: sedimentary ...

channel flows have three components of velocity, 1component in flow direction and 2components in spanwise of channel. because of heterogeneity of velocity undulations, in the channel section the vortices are formed that are nominated “secondary current cells”. these cells cause the lateral shear stress in the channel walls and introduce the erosion and scour of the channel walls. heterogeneity ...

[1] A time domain Boussinesq model for nearshore hydrodynamics is improved to obtain the conservation of vertical vorticity correct to second order and extended for use on an open coast using longshore periodic boundary conditions. The model is utilized to simulate surface waves and longshore currents under laboratory and field conditions. Satisfactory agreement is found between numerical resul...

in this theoretical study, the effect of various types of bypass graft angles on the flow field, has been investigated specially on the temporal wall shear stress (wss) on the toe, heel and some locations on the bed of the left anterior descending (lad) artery at the anastomoses areas in the aorto-coronary (ac) and coronary-coronary (cc) bypasses. flow fields in both bypasses with angles of 20º...

Traditional bed shear stress-based models (e.g., Rouse model) derived from the classic parabolic profile of eddy viscosity in open-channel flows fail to accurately predict suspended sediment concentration (SSC) with aquatic vegetation. We developed a two-layer, turbulence-based model SSC profiles emergent vegetated flows. Turbulence generated vegetation, bed, and coherent structures caused by s...