Modelling and simulation of multiscale systems constitutes a grand challenge in computational science, and is widely applied in fields ranging from the physical sciences and engineering to the life sciences and the socio-economic domain. To adequately simulate numerous intertwined processes characterized by different spatial and temporal scales (often spanning many orders of magnitude), sophist...

Virtual Reality is an exciting new area of human-computer interaction. Its use depends critically on having extremely low response times of the virtual environment to user interaction. The problem of reducing the lag between the user’s head position or orientation changing and the updating of the displayed view has been described as one of the grand challenges of computing. The techniques descr...

Informatik ist mittlerweile ubiquitär, auch oder vielleicht gerade in der Landwirtschaft. Das Interesse an der Agrarinformatik stagniert dagegen eher, ist vielleicht sogar rückläufig. Indizien hierfür sind die Mitgliederzahlen der GIL aber auch Streichungen von Professuren mit dem Schwerpunkt Agrarinformatik an Universitäten, wie zuletzt im Jahre 2012 in Kiel. Es scheint somit eine Diskrepanz z...

Overview: Science is arguably the pinnacle of human intellectual achievement, yet the scientific discovery process itself remains an art. Human intuition and experience are still the driving forces of the high-level discovery process: we determine which hypotheses and theories to entertain, which experiments to conduct, how data should be interpreted, when hypotheses should be abandoned, and so...

Introduction & Motivation As evidence in support of anthropogenic climate change continues to mount [1], the study of climate has become a focus of scientific research, political attention, and socioeconomic concern. There are many different aspects to studying climate, from the collection and analysis of historical/observed data to the understanding of current climate and its underlying physic...

“Space drives,” “Warp drives,” and “Wormholes:” these concepts may sound like science fiction, but they are being written about in reputable journals. To assess the implications of these emerging prospects for future spaceflight, NASA supported the Breakthrough Propulsion Physics Project from 1996 through 2002. This project has three grand challenges: (1) Discover propulsion that eliminates the...

Management on inter-enterprise collaborations (business networks) still face grand challenges especially in terms of managing interoperability of nonfunctional properties (NFPs) at various levels (technical, semantic, pragmatic). This paper identifies three categories of nonfunctional properties (collaborative for business level, contractual for communication issues, extrafunctional for computa...

The increasing scale complexity, heterogeneity and dynamism of networks, systems and applications have made our computational and information infrastructure brittle, unmanageable and insecure. This has necessitated the investigation of an alternate paradigm for system and application design, which is based on strategies used by biological systems to deal with similar challenges – a vision that ...

oral cancer has emerged as a significant cause of global public health concern in both developing and developed nations. multiple socio-demographic and habit-related risk factors have been attributed to causing oral cancer. a diverse array of challenges exists in the global campaign to address the burden of oral cancer. such challenges have served as barriers to the early diagnosis and treatmen...