Alkylthio benzene derivatives were effectively synthesized by simultaneous diazotization of aromatic amines and nucleophilic displacement. The method is fairly general proceeds in moderate yields. Product yields comparable regardless steric hindrance the thiol or functional group present starting material. newly developed procedure allowed for incorporation a tertiary alkylthio group, which can...

The synthesis of novel bis(3-carbazoly1)methane linked bis-benzimidazoles is described. Construction symmetrical on the bis-carbazolylmethane scaffold was succeeded by condensation reaction benzene-1,2-diamine derivatives with bis(9-ethyl-9H-carbazole-3-carbaldehyde). structural analysis targeted compounds 4-7 were confirmed NMR, FT-IR spectroscopy and mass spectrometry. thermal stability final...

cancer is a leading cause of death worldwide. despite the availability of several chemotherapeutic drugs, there is still a great need for more efficient agents for a better management of cancer. in this contribution, a series of 11 dhps (4a, 4b & 7a-i) were synthesized and evaluated for their cytotoxic effect against mcf-7, ls180, and molt-4 cancer cell lines using mtt assay. synthesized 2,6-di...

This study includes synthesis and characterization of new derivatives 3-(2-(6-oxo-1,3-thiazinan-3-yl)-R)-1,3-oxazepane-4,7-dione N-Bromo amines 1,3-oxazepane-4,7-dione derivatives. Schiff's bases reactions through one step process in inert solvents. Some employing [1- 4]; addition, synthesized by the reaction different with (Salicylaldehyde) absolute ethanol under reflux. Heterocyclic rings pre...

H an s B o ck 3*, W olfgang Seitz3, N o rb e rt N agel3, R ü d ig er B a u rb, Jan W. B a ts3, Z d e n e k H av la sc, R odney F. C. C laridged a Chemische Institute der Universität Frankfurt, Marie-Curie-Str. 11, D-60439 Frankfurt am Main b Hoechst AG, Postfach 800320, D-65926 Frankfurt/Main c Institut für Organische Chemie und Biochemie, Tschechische Akademie der Wissenschaften, Flemingova Na...

Surfactants are adaptable amphiphilic compounds have an especially distinctive polar hydrophilic head and non-polar tail group. The surfactant is extensively used in each walk of life such as care products, domestic cleaners, pharmaceuticals, oil recovery, food handling, nanotechnologies due to decreasing the interfacial tension,. Micellization anionic surfactants potassium dodecyl sulphate (KD...