The mol-ecule of the title compound, C(14)H(9)N(3), is essentially planar, the dihedral angle formed by the benzimidazole ring system with the benzene ring being 3.87 (3)°. In the crystal packing, mol-ecules are linked into zigzag chains running parallel to the b axis by inter-molecular N-H⋯N hydrogen-bond inter-actions.

In the title compound, C(27)H(23)N(3)O·H(2)O, the benzimidazole ring system has an r.m.s. deviation of 0.0071 Å and makes dihedral angles of 34.51 (2), 55.22 (3) and 41.05 (5)° with the central and N-bonded phenyl rings, respectively. In the crystal, the water mol-ecular is connected to the organic mol-ecule by inter-molecular O-H⋯N hydrogen bonds. Weak inter-molecular C-H⋯O hydrogen bonds also...

The asymmetric unit of the title compound, C(26)H(32)N(4)O(4), consists of two independent mol-ecules. In both mol-ecules, the eth-oxy groups are each disordered over two sets of sites with occupancies of 0.695 (4):0.305 (4) and 0.877 (2):0.123 (2). The dihedral angles between the benzimidazole ring system and the adjacent benzene ring in the two mol-ecules are 41.41 (5) and 31.46 (5)°. In the ...

In the title compound, C(12)H(13)N(3)O(2)S, the oxazolidin ring displays an envelope conformation. The dihedral angle between the benzimidazole ring and the 1,3-oxazolidin-2-one mean plane is 69.85 (13)°. In the crystal, mol-ecules are linked by inter-molecular N-H⋯N hydrogen bonds, forming a chain parallel to the b axis.

The comparative antifungal activity of four benzimidazole compounds was determined against 11 fungi.

A series of (benzamidostyryl)benzimidazole derivatives were synthesized by hydrolyzing 2-phenyl-4-(substituted)benzylidene-5-oxazolones, the azlactone precursors in an acidic medium and treating the product with substituted o-phenylenediamine (OPDA) in situ. The structures of the synthesized compounds were confirmed by spectral and elemental analyses. All synthesized compounds were screened for...

Strongyloides stercoralis infections have a worldwide distribution with a global burden in terms of prevalence and morbidity that is largely ignored. A public health response against soil-transmitted helminth (STH) infections should broaden the strategy to include S. stercoralis and overcome the epidemiological, diagnostic, and therapeutic challenges that this parasite poses in comparison to As...

Phenolyl cobamides are unique members of a class of cobalt-containing cofactors that includes vitamin B12 (cobalamin). Cobamide cofactors facilitate diverse reactions in prokaryotes and eukaryotes. Phenolyl cobamides are structurally and chemically distinct from the more commonly used benzimidazolyl cobamides such as cobalamin, as the lower axial ligand is a phenolic group rather than a benzimi...

Analysis of structure-activity relationships in the inhibition of influenza B vir'us multiplication by benzimidazoles has led to the synthesis of new derivatives (Tamm et al., 1956) having 1,000 times the activity of compounds first studied (Tamm et al., 1952; Tamm et al., 1953c). A considerable difference in selectivity of action between 2, 5-dimethylbenzimidazole (MB) and 5, 6 dichloro 1 -/3D...

A survey to study the extent of anthelmintic resistance was conducted in Maputo and Gaza, two of the ten provinces of Mozambique, during February and March, 1999. A total of 12 flocks, six in Maputo and six in Gaza, was surveyed. The faecal egg count reduction test was used to assess the efficacy of three anthelmintics most often used in Mozambique, namely albendazole, fenbendazole and levamiso...