نتایج جستجو برای: benzoapyrene bap

تعداد نتایج: 3093  

2012
Sourav Bhattacharya J. Angayarkanni Arijit Das M. Palaniswamy

Benzo[a]pyrene (BaP) is a ubiquitous environmentally significant compound which due to its recalcitrant nature is often referred as persistent bioaccumulative toxin. The present study was carried on to determine the degradation potentials of three natural isolates of the white rot fungi Pleurotus ostreatus towards BaP, of which isolate PO-3 showed promising results. The factors affecting biodeg...

Journal: :Clinical biochemistry 2014
Etienne Cavalier Jean-Claude Souberbielle Romy Gadisseur Bernard Dubois Jean-Marie Krzesinski Pierre Delanaye

BACKGROUND Bone-specific alkaline phosphatase (BAP) is now recommended to assess bone turnover in hemodialysis (HD) patients. However, little is known about potential variability between methods available to measure BAP. METHODS We measured BAP in 76 HD patients with six different assays (Beckman-Coulter Ostase IRMA, Beckman-Coulter Ostase Access, IDS iSYS Ostase, IDS Ostase enzyme immunoassa...

2016
Tawny Tsang Kristen Gillespie-Lynch Ted Hutman

Subclinical variants of the social-communicative challenges and rigidity that define autism spectrum disorder (ASD) are known as the broader autism phenotype (BAP). The BAP has been conceptualized categorically (as specific to a subset of relatives of individuals with ASD) and dimensionally (as continuously distributed within the general population). The current study examined the compatibility...

Journal: :Drug metabolism and disposition: the biological fate of chemicals 2006
Thomas Walle U Kristina Walle David Sedmera Mitch Klausner

Oral cancer, originating from smoking-induced lesions of the basal cells in the complex stratified oral epithelium, is difficult to treat. Early detection of premalignant lesions, e.g., leukoplakia, has suggested the possibility of chemopreventive measures, such as topical application of antimutagenic/antiproliferative dietary or pharmaceutical agents. As an extension of a study in human oral e...

2006
M. A. Pereira F. J. Burns R. E. Albert

The dose dependency of the binding of benzo(a)pyrene (BaP) with DNA of mouse epidermis was investigated. BaP conjugated epidermab DNA was isolated and enzymatically degraded to deoxyribonucleosides. The BaP-DNA adducts were separated by Sephadex LH-20 column or high-perform ance liquid chromatography. Two major BaP-DNA adducts were found. One was in the region of the ebution profile that contai...

2017
Xi Chen Hongbing Peng Jian Xiao Anqi Guan Bin Xie Bixiu He Qiong Chen

Benzo(a)pyrene (BaP), an important toxic component of cigarette smoke, can cause lung cancer and lead to the progression of lung cancer. In the present study, we investigated the effect of BaP on the migration of lung adenocarcinoma A549 cells. BaP (1 µM) promoted the migration of A549 cells in a time-dependent manner and upregulated the expression of the Twist family BHLH transcription factor ...

Journal: :Toxicological sciences : an official journal of the Society of Toxicology 2002
Rola Barhoumi Youssef Mouneimne Igbal Awooda Stephen H Safe Kirby C Donnelly Robert C Burghardt

Intracellular Ca2+ oscillations induced by oxytocin and vasopressin were analyzed in a rat liver cell line (Clone 9) in order to identify mechanisms by which benzo[a]pyrene (BaP) alters Ca2+ signaling patterns in these cells. Clone 9 cells exhibit an initial Ca2+ spike, followed by Ca2+ oscillations upon oxytocin or vasopressin treatment. The range of frequencies (maximum 110 mHz) was dependent...

Journal: :The American journal of physiology 1998
Beek Yoke Chin Mary E Choi Marie D Burdick Robert M Strieter Terence H Risby Augustine M K Choi

Particulate matter (PM) is a major by-product from the combustion of fossil fuels. The biological target of inhaled PM is the pulmonary epithelium and resident macrophages. In this study, we demonstrate that cultured macrophages (RAW 264.7 cells) exposed continously to a well-defined model of PM [benzo[ a]pyrene adsorbed on carbon black (CB+BaP)] exhibit a time-dependent expression and release ...

2017
Ling CAO Shaoping KUANG Jinghuan ZHANG Huihui WANG Jun WAN

Cao L., Kuang S., Zhang J., Wang H., Wan J. (2018): Comparative sorption and desorption of benzo[α]pyrene and 1,2,3-trichlorobenzene by biochar in the presence of dissolved organic matter. Soil & Water Res. Sorption and desorption of benzo[α]pyrene (BaP) and 1,2,3-trichlorobenzene (TrCB) on biochar prepared from maple wood shavings heated at 500°C were studied in the presence of dissolved organ...

2010
Maria Teresa Piccardo Anna Stella Federico Valerio

BACKGROUND Very few studies have evaluated the adverse effect of passive smoking exposure among active smokers, probably due to the unproven assumption that the dose of toxic compounds that a smoker inhales by passive smoke is negligible compared to the dose inhaled by active smoke. METHODS In a controlled situation of indoor active smoking, we compared daily benzo(a)pyrene (BaP) dose, estima...

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