The linear interaction energy (LIE) method is combined with energy minimization and finite-difference Poisson calculation of electrostatic solvation for the estimation of the absolute free energy of binding. A predictive accuracy of about 1.0 kcal/mol is obtained for 13 and 29 inhibitors of beta-secretase (BACE) and HIV-1 protease (HIV-1 PR), respectively. The multiplicative coefficients for th...

We consider a Callan–Symanzik and a Wilson Renormalization Group approach to the infrared problem for interacting fermions in one dimension with backscattering. We compute the third order (two–loop) approximation of the beta function using both methods and compare it with the well known multiplicative Gell–Mann Low approach. We point out a previously unnoticed qualitative dependence of the thir...

Spatial fluctuations in microwave backscatter may be an important piece of information in discriminating tree stands. However, the presence of speckle in synthetic aperture radar (SAR) image data is a barrier to the exploitation of image texture. We explored a new methodology that combines a recent adaptive speckle reduction algorithm by Lopes et al. [12] with a generic texture estimation schem...

Separated Component-Based Restoration of Speckled SAR Images Report Title Many coherent imaging modalities such as Synthetic Aperture Radar (SAR) suffer from a multiplicative noise commonly referred to as speckle which often makes the interpretation of data difficult. An effective strategy for speckle reduction is to use a dictionary that can sparsely represent the features in the speckled imag...

The gene for beta-amylase was isolated from Bacillus polymyxa by molecular cloning in B. subtilis. B. subtilis cells containing this gene express and secrete an amylase which resembles the B. polymyxa beta-amylase and barley beta-amylase in terms of the products it generates during carbohydrate hydrolysis. Starch hydrolysis with this beta-amylase produces maltose, not glucose, whereas maltotrio...

The gene for beta-amylase was isolated from BacUlus polymyxa by molecular cloning in B. subtils. B. subtlis cells containing this gene express and secrete an amylase which resembles the B. polymyxa beta-amylase and barley beta-amylase in terms of the products it generates during carbohydrate hydrolysis. Starch hydrolysis with this beta-amylase produces maltose, not glucose, whereas maltotriose ...

Strongly multiplicative linear secret sharing schemes (LSSS) have been a powerful tool for constructing secure multi-party computation protocols. However, it remains open whether or not there exist efficient constructions of strongly multiplicative LSSS from general LSSS. In this paper, we propose the new concept of 3-multiplicative LSSS, and establish its relationship with strongly multiplicat...

Abstract Consider the complete graph on n vertices. To each vertex assign an Ising spin that can take values $$-1$$ - 1 or $$+1$$ + . Each $$i \in [n]=\{1,2,\dots , n\}$$ i ∈ [ n <mml:m...

We prove that the topological statement: “Any compact covering mapping between two Borel sets is inductively perfect” is equivalent to the set-theoretical statement: “ ∀α ∈ ωω , א 1 < א1”. The starting point of this work is the following topological problem: Problem. Is any compact covering mapping between two Borel spaces inductively perfect? We recall that if f : X → Y is a continuous and ont...