background: ovarian cancer comprises a heterogeneous group of neoplasms. the prognosis cannot be predicted by histopathologic examination alone. the aim of this study is to evaluate p53, pten, and β-catenin expressions in primary ovarian carcinomas in an attempt to find a possible relationship with morphologic parameters and clinical findings. methods: the study included 100 epithelial ovarian ...

OBJECTIVES Subjective ultrasonographic assessment is currently considered to be the best method of differentiation between various types of ovarian tumors. The aim of the study was to evaluate selected ultrasonographic features and CA125 levels of hormonally active ovarian tumors. MATERIAL AND METHODS A total of 1135 women with ovarian tumors were diagnosed between 2006 and 2014 at the Divisi...

Background: Borderline Ovarian tumor are epithelial tumors, diagnosed in early stage with excellent prognosis. The risk of recurrence is matter concern. Methods: A retrospective, cross-sectional study conducted at OBGYN department Aga khan hospital Karachi from 2002 to 2018. Results: Seventy-three patients BOT were enrolled mean age 40 years. Fertility sparing surgery (FSS) was performed 35 (48...

INTRODUCTION Uterine tumors resembling ovarian sex cord tumors (UTROSCT) are uterine neoplasms of unknown histiogenesis which show near complete differentiation towards ovarian sex cord elements and are postulated to arise from pluripotential uterine mesenchymal cells or endometrial stromal cells with secondary sex cord differentiation. CASE PRESENTATION A 48 year old post-menopausal women pr...

Abstract Background: Leydig cell tumors account for less than 0.1% of all ovarian and are usually unilateral benign. They present mostly in postmenopausal women with symptoms hyperandrogenism. On the other hand, primary hyperparathyroidism (PHPT) is a relatively common endocrine disorder, prevalence one to seven cases per 1,000 adults. It most commonly presents as an isolated, sporadic clinical...

We present a unique case of incidentally discovered bilateral Sertoli Leydig cell tumour in a primigravida who displayed no features of virilization. The apha fetoprotein levels were elevated. Magnetic resonance imaging was suggestive of ovarian tumors, possibly germ cell tumor. Bilateral salpingo-oophorectomy was performed and histopathology showed features of Sertoli Leydig cell tumor with in...

Ovarian metastatic tumors represents up to 10% of all ovarian malignancies. The most encountered tumors which may give birth to ovarian cancer are those originating from the gastric tube; however, other malignancies such as breast, cervix, lung or even skin may be associated with ovarian metastatic tumors. This is a literature review of the most frequently seen ovarian metastatic tumors.

Markers that reliably identify cancer stem cells (CSC) in ovarian cancer could assist prognosis and improve strategies for therapy. CD133 is a reported marker of ovarian CSC. Aldehyde dehydrogenase (ALDH) activity is a reported CSCmarker in several solid tumors, but it has not been studied in ovarian CSC. Here we report that dual positivity of CD133 and ALDH defines a compelling marker set in o...