With the advent of high throughput data genomic technologies the volume of available data is now staggering. In addition databases that provide resources to annotate, translate, and connect biological data have grown exponentially in content and use. The availability of such data emphasizes the importance of bioinformatics and computational biology in genomics research and has led to the develo...

Protein structure classification represents an important process in understanding the associations between sequence and structure as well as possible functional and evolutionary relationships. Recent structural genomics initiatives and other high-throughput experiments have populated the biological databases at a rapid pace. The amount of structural data has made traditional methods such as man...

Continued advancements in sequencing technologies have fueled the development of new sequencing applications and promise to flood current databases with raw data. A number of factors prevent the seamless and easy use of these data, including the breadth of project goals, the wide array of tools that individually perform fractions of any given analysis, the large number of associated software/ha...

The PLMItRNA database contains information and multialignments of tRNA genes and molecules detected in higher plant mitochondria. It has been developed from a previous compilation of higher plant mitochondrial tRNA genes [Sagliano,A., Volpicella,M., Gallerani,R. and Ceci,L.R. (1998) Nucleic Acids Res., 26, 154-155] and implemented with data and sequences of tRNA molecules retrieved from the lit...

As part of an environmental observation and forecasting system, sensors deployed in the Columbia RIver Estuary (CORIE) gather information on physical dynamics and changes in estuary habitat. Of these, salinity sensors are particularly susceptible to biofouling, which gradually degrades sensor response and corrupts critical data. Automatic fault detectors have the capability to identify bio-foul...

Sequencing the human genome began in 1994, and 10 years of work were necessary in order to provide a nearly complete sequence. Nowadays, NGS technologies allow sequencing of a whole human genome in a few days. This deluge of data challenges scientists in many ways, as they are faced with data management issues and analysis and visualization drawbacks due to the limitations of current bioinforma...

The aim of the Journal of Integrative Bioinformatics (JIB) is to provide a free-of-charge open access and peer-reviewed platform for original research articles in all aspects of integrative bioinformatics. Over the last ten years, the editorial board accompanied the process and trends in integrative bioinformatics and perceives a strong tendency towards a glut of tools and databases. As a conse...