The effects of alpha-ketoglutarate (alpha-KG) on ethanol-induced hepatotoxicity were studied in biochemical experiments in rats. The levels of serum transaminases and thiobarbituric acid reactive substances were significantly increased in ethanol-treated rats. These levels were significantly decreased in alpha-KG- and ethanol-treated rats. Further, non-enzymatic (vitamins C and E) and enzymatic...

Hepatoprotective activity of the ethyl acetate extract of Teucrium polium L. was investigated using rats with CCl4-induced liver damage. Specific biochemical parameters (glutathione peroxidase, superoxide dismutase, reduced glutathione and total antioxidative status) were estimated in blood and in liver homogenate. Lipid peroxidation in CCl4-intoxicated rats was evidenced by a marked increment ...

Computer assisted analysis and simulation of biochemical pathways can improve the understanding of the structure and the dynamics of these systems considerably. The construction and quantitative analysis of kinetic models is often impeded by the lack of reliable data. However, as the topological structure of biochemical systems can be regarded to remain constant in time, a qualitative analysis ...

Experiments were conducted to understand the therapeutic properties such as anti-inflammatory, anti-oxidative, haematological and serum biochemical markers of earthworm paste (EP) derived from an indigenous species Lampito mauritii (Kinberg), in comparison with the standard anti-inflammatory drug- aspirin, on Wistar albino rat (Rattus norvegicus). Administration of earthworm paste of Lampito ma...

Computer assisted analysis and simulation of biochemical pathways can improve the understanding of the structure and the dynamics of cell processes considerably. The construction and quantitative analysis of kinetic models is often impeded by the lack of reliable data. However, as the topological structure of biochemical systems can be regarded to remain constant in time, a qualitative analysis...

Litchi is a tasty fruit that is commercially grown for food consumption and nutritional benefits in various parts of the world. Due to its biological activities, the fruit is becoming increasingly known and deserves attention not only for its edible part, the pulp, but also for its peel and seed that contain beneficial substances with antioxidant, cancer preventive, antimicrobial, and anti-infl...

Carbon tetra chloride (CCl4) induced acute hepatotoxicity causes severe damage to hepatocytes and affects the liver functions which resemble various liver ailments like hepatitis, jaundice, cancer etc. Using 12-different fruits, formulation F1 and F2 were prepared. Hepatoprotective potential of the formulations was assessed using HepG2 cell (in vitro) and rat model (in vivo). Biochemical parame...

The effects of alpha-ketoglutarate (alpha-KG) on sodium valproate-induced hyperammonemia and hepatotoxicity were studied in biochemical experiments in rats. The levels of ammonia, urea, serum transaminases, hydroperoxides and thiobarbituric acid reactive substances were significantly increased in sodium valproate-treated rats. These levels were significantly decreased in alpha-KG- and sodium va...

115 samples of honey various botanical types, geographical origin and harvest year (2019– 2021) were analysed using attenuated total reflection infrared spectroscopy impaired reflection, refractometry biochemical analysis. Initial in liquid crystallised states investigated. Crystalline D-glucopyranose (glucose), D-fructopyranose (fructose), their 40% solutions invert sugar used as auxiliary sub...

Introduction Schizophrenia (SZ) is an inherited mental illness that affects 1% of the world’s population. a common functional psychosis with some unifying features appears to have universal distribution. Much research on SZ seeks identify physiological, biochemical, or genetic differ between patients and healthy individuals. Biochemical factors represent imbalance certain biochemical substances...