Single-Cell Proteomics Single-cell proteomics provides an unprecedented view of cellular heterogeneity at the single-cell resolution, enabling a better understanding biological mechanisms. In article number 2207061, Ying Zhang, Huaicheng Sun, Feng Zhu, and co-workers develop ANPELA, significantly enhanced quantification tool that facilitates analysis high-dimensional proteome expression data id...

background: cd52 is a small glycoprotein with a gpi anchor at its c-terminus. cd52 is expressed by normal and malignant t and b lymphocytes and monocytes. there are detectable amounts of soluble cd52 in plasma of patients with cll and could be used as a tumor marker. although the biological function of cd52 is unknown but it seems that cd52 may be involved in migration and activation of t-cells...

Background: The induction of bystander effect via ionizing radiation has been well proven. However, few studies have investigated the bystander effect following non-ionizing radiation, such as ultrasound waves. Here, the bystander effect after different sonication times on human melanoma cell line (A375), is evaluated by assessing cell viability and apoptosis. Materials and Methods: The cells w...

abstract these days, scientsts search for cheap protein sources because of growthing of population.one of these sources is single cell protein.this study deals with single cell protein production process by saccharomyces cerevisiae and saccharomyces carlsbergensis .these yeast are known as the most ideal and practical eukaryotic microorganism in biological studies. in this survey we added the w...

a new series of 1,2-diaryl-4,5,6,7-tetrahydro-1h-benzo[d]imidazoles, possessing trimethoxy phenyl pharmacophore, were synthesized to evaluate their biological activities as tubulin inhibitors. cytotoxic activity of the synthesized compounds 7a-f was assessed against several human cancer cell lines, including mcf-7 (breast cancer cell), hepg2 (liver hepatocellular cells), a549 (adenocarcinomic h...

introduction: attachment of blood and tissue cells to the extracellular matrix (ecm) is done with the help of specific joints, which are made between cells’ receptors and matrixes’ ligands. this interaction is vital for many biological activities such as cell migration, cancer development, and wound healing. the purpose of this study is to model a 3-dimensional cell by abaqus commercial softwar...