Metabonomics/metabolomics is an important science for the understanding of biological systems and the prediction of their behaviour, through the profiling of metabolites. Two technologies are routinely used in order to analyse metabolite profiles in biological fluids: nuclear magnetic resonance (NMR) spectroscopy and mass spectrometry (MS), the latter typically with hyphenation to a chromatogra...

Fourier Transform Infra Red (FTIR) Spectroscopy is a non-invasive, reagent free diagnostic tool in the analysis of biological fluids. The results can be best employed in the qualitative and quantitative investigation of biological fluids. Multiple myeloma is a disorder in which malignant plasma cells accumulate in bone marrow and produce excess immunoglobulin that leads to many complications. T...

Salvinorin A is a novel hallucinogen isolated from the widely available leaves of Salvia divinorum. Based on its mechanism of action, salvinorin A has shown potential as a stimulant abuse therapeutic. However, there are no methods for the detection of salvinorin A or its metabolites in biological fluids. In order to begin developing salvinorin A as a potential therapeutic, an understanding of i...

BACKGROUND Orally administered particles rapidly interact with biological fluids containing proteins, enzymes, electrolytes, and other biomolecules to eventually form particles covered by a corona, and this corona potentially affects particle uptake, fate, absorption, distribution, and elimination in vivo. This study explored relationships between the biological interactions of calcium carbonat...

A new sensitive, simple and rapid method for determination of methotrexate (MTX) was developed based on quenching effects of MTX on the fluorescence intensity of Tb3+-1,10-phenanthroline complex. The fluorescence intensity was measured with excitation wavelength of 300 nm and emission wavelength of 545 nm and the quenched fluorescence intensity is proportional to the concentration of MTX in Tris...

pathological changes within an organ can be reflected as proteomic patterns in biological fluids such as plasma, serum, and urine. the surface-enhanced laser desorption and ionization time-of-flight mass spectrometry (seldi-tof ms) has been used to generate proteomic profiles from biological fluids. mass spectrometry yields redundant noisy data that the most data points are irrelevant features ...

a new sensitive, simple and rapid method for determination of methotrexate (mtx) was developed based on quenching effects of mtx on the fluorescence intensity of tb3+-1,10-phenanthroline complex. the fluorescence intensity was measured with excitation wavelength of 300 nm and emission wavelength of 545 nm and the quenched fluorescence intensity is proportional to the concentration of mtx in tris...

Fluids are present throughout Earth’s crust and act as a primary medium of exchange between Earth’s interior lithosphere and hydrosphere Flowing fluids carry enormous fluxes of energy magma and solutes be tween these reservoirs Fluids contribute to production of continental crust generation of explosive volcanism lubrication of plate boundary faults formation of hydrates and mineral resources a...

Silver (AgNPs) and maghemite, i.e., superparamagnetic iron oxide nanoparticles (SPIONs) are promising candidates for new medical applications, which implies the need for strict information regarding their physicochemical characteristics and behavior in a biological environment. The currently developed AgNPs and SPIONs encompass a myriad of sizes and surface coatings, which affect NPs properties...

Fachinternes Symposium: " Dynamics of multi-component fluids " Organisation: Fachinternes Symposium: " Polymer networks and beyond: From molecular structure to materials and biological functions " Organisation: