Phamacokinetics is proposed to study the absorption, the distribution, the biotransformations and the elimination of drugs in man and animals. A single kinetic profile may be well summarized by Cmax, Tmax, t 1/2 and AUC and, having more than one profile, 8 parameters at least, the mean and standard deviation of these parameters, may well summarize the drug kinetics in the whole population. A mo...

Probabilistic Neural Networks (PNNs) constitute a promisingmethodology for classification and prediction tasks. Their performance depends heavily on several factors, such as their spread parameters, kernels, and prior probabilities. Recently, Evolutionary Bayesian PNNs were proposed to address this problem by incorporating Bayesian models for estimation of spread parameters, as well as Particle...

β-Hydroxy-β-methylbutyrate (HMB), a leucine metabolite, has long been supplemented as a Ca salt (Ca-HMB) to increase strength and performance gains with exercise and to reduce recovery time. Recently, the free acid form of HMB (HMB-FA) has become commercially available in capsule form (gelcap). The current study was conducted to compare the bioavailability of HMB using the two commercially avai...

AIM To analyse the correlation between (18)F-FDG uptake assessed by PET/CT in locally advanced breast tumours and histopathological and immunohistochemical prognostic factors. MATERIAL AND METHODS Thirty-six women with breast cancer were prospectively evaluated. PET/CT was requested in the initial staging previous to adjuvant chemotherapy (multicentric study). All the patients underwent an (1...

Biological fertilizers are compounds comprising various free living microorganisms that are able to change the basic nutrients into available form through biological procedures. Being an important source of nutrients in sustainable agriculture, these fertilizers lead to better seed germination and development of root system. In order to investigate the effect of biological fertilizers on the me...

Background: To determine the role of drugs in fatal overdose, analyses were done on samples obtained from autopsy examination and death and crime scene investigations. The aim of this study was to evaluate the usefulness of toxicology analyses of postmortem biological and non-biological samples belonging to a subject in determining the forensic cause of death. Methods: Toxicological analysi...

One of the ordinary methods to protect, rehabilitate, and enhance an ecosystemfunction in arid and semi-arid areas of the world is sand dune stabilization using biologicalpractices. Plantation of species on the soil plays a great role in sustainable management ofthe ecosystem. This research studies the effects of cultivation of Haloxylon ammodendronand Atriplex canescens on physical-chemical ch...

The use of polarimetric techniques is nowadays widespread among solar and stellar astronomers. However, notwithstanding the recommandations that have often been made about the publication of polarimetric results in the astronomical literature, we are still far from having a standard protocol on which to conform. In this paper we review the basic definitions and the physical significance of the ...