We present heuristics to compute multiple watchmen routes. Given a polygon (with or without holes) and a parameter k, we compute a set of k routes inside the polygon such that any point inside the polygon is visible from at least one point along one route. We measure the quality of our solutions by either the length of the longest route and the sum of route lengths, where the goal is to minimiz...

The article aims to analyze the progress of evolution cinnamic acid derivatives through a bibliographic review, describing main synthetic routes in obtaining this class, as well remarkable biological applications and application structure-activity relationship (SAR) strategy for design pharmacologically active molecules. methodology used consists reading analyzing articles, whose approach is de...

The aim of this review is to provide information regarding significant aspects and challenges in developing nasal sprays. This article outlined the relevant anatomy, physiology & biological, physicochemical pharmaceutical factors that must be considered during formulation development Nasal drug delivery system most preferable route than other routes administration as it gives rapid onset ac...