Abstract Physcion is an anthraquinone compound observed dominantly in medicinal herbs. This possesses a variety of pharmaceutically important activities and has been developed to be widely used antifungal biopesticide. Herein, we report on the effective preparation 3R -torosachrysone ( 4 ), tetrahydroanthracene precursor physcion, Aspergillus oryzae NSAR1 by heterologous expression related gene...