This CIBA Symposium on the intestinal mucosa represents a timely review of dissecting, light, and electron microscopic studies of the small bowel. Booth, et al. describes dissecting microscopic changes in the small bowel, some of which could not be appreciated by the light microscope. The dissecting microscope appears to be widely employed by the British and Europeans, but neglected by the Amer...

Nonfocal liver biopsy may be required to diagnose or stage diffuse parenchymal dis• ease such as cirrhosis, viral hepatitis, autoimmune hepatitis, primary biliary cirrhosis, primary sclerosing cholangitis, hemachromatosis, and Wilson’s disease. Focal liver biopsy may be necessary to diagnose or stage primary or secondary hepatic • malignancy and to differentiate malignancy from benign hepatic m...