Bisphenol A (BPA) is a xenoestrogen known for its implications the endocrine systems and several other organs, including kidneys. Recent renal studies have shown that BPA can induce alterations of cytoskeleton cell adhesion mechanisms such as podocytopathy with proteinuria hypertension, involved in progression diseases. These data fact to be present urine almost entire population strongly sugge...

Objective(s): Since bisphenol A (BPA) induces bone loss and phytoestrogens enhance the osteoblastogenesis by binding to the non-classical and classical oestrogen receptors, respectively, the present study was aimed to observe the osteoprotective effect of phytoestrogens on BPA-induced osteoblasts in hFOB 1.19 cells.Materials and Methods:...

The widespread human exposure to bisphenol A (BPA), an endocrine disruptor targeting developmental processes, underlines the need to better understand the mechanisms of fetal exposure. Animal studies have shown that at a late stage of pregnancy BPA is efficiently conjugated by the fetoplacental unit, mainly into BPA-glucuronide (BPA-G), which remains trapped within the fetoplacental unit. Fetal...

In recent years, the association between alterations in animal hormonal regulation and exposure to estrogenic endocrine – disrupting chemicals (EEC), such as xenoestrogens has led to increasing public and scientific concern. EEDs reportedly have the potential to produce widespread adverse effects through their endocrine disrupting activity, such as carcinogenicity, neurotoxicity, immunotoxicity...

The simultaneous determination of trace amounts of endocrine disruptors such as bisphenol A (BPA) and its monochloro, dichloro, trichloro and tetrachloro derivatives in wastewater has been developed using gas chromatography-mass spectrometry (GC-MS). Compounds were previously extracted from the aqueous samples using a liquid-liquid extraction procedure with a mixture of dichloromethane:carbon t...

Background & Objective:  Bisphenol A (BPA) is a hazardous environmental pollutant, which is known to cause ovarian toxicity. The present study aimed to assess the protective effects of Aloe vera herbal extract against ovarian toxicity caused by BPA in Wistar rats. Materials & Methods:  The sample population of this experimental study consisted of 40 adult female Wistar rats with a mean weight ...

The widespread human exposure to bisphenol A (BPA), an endocrine disruptor targeting developmental processes, underlines the need to better understand the mechanisms of fetal exposure. Animal studies have shown that at a late stage of pregnancy BPA is efficiently conjugated by the fetoplacental unit, mainly into BPAglucuronide (BPA-G), which remains trapped within the fetoplacental unit. Fetal ...

This study presents results of the effects of bisphenol A (BPA) on adult egg production, egg hatchability, egg development rates and juvenile growth rates in the freshwater gastropod, Marisa cornuarietis. We observed no adult mortality, substantial inter-snail variability in reproductive output, and no effects of BPA on reproduction during 12 weeks of exposure to 0, 0.1, 1.0, 16, 160 or 640 mic...

Bisphenol A (BPA) is one of the most common endocrine disrupters. In the last decade, the number of studies concerning the effects of chronic treatment with BPA on the development of the central nervous system (CNS) has increased. However, little is known about the effects of chronic exposure to BPA on higher brain functions such as memory or psychomotor functions. Here, we report our following...