نتایج جستجو برای: bisulfite sequencing
تعداد نتایج: 128044 فیلتر نتایج به سال:
Medical Genomics, UCL Cancer Institute, University College London, London WC1E 6BT, UK Centro Nacional de Análisis Genómico (CNAG), Parc Científic de Barcelona, Torre I, 08028 Barcelona, Spain Division of Surgery and Interventional Science, University College London, London W1W 7EJ, UK Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Harvard Stem Cell Institute, Cambridge, MA 02138...
We describe a suite of predictive models, coined FAST(m)C, for nonreference, cost-effective exploration and comparative analysis of context-specific DNA methylation levels. Accurate estimations of true DNA methylation levels can be obtained from as few as several thousand short-reads generated from whole-genome bisulfite sequencing. These models make high-resolution time course or developmental...
Breast cancer is one of the world’s most prevalent among women. Globally approximately 2.3 million women are diagnosed with breast in 2020. It arises due to epigenetic modification which outlooks aberrant methylation as its major cause. The DNA involves a covalent chemical drawback, promoting development cancer. In addition, evidence and investigation suggest that these methylations at promoter...
Social insects are promising model systems for epigenetics due to their immense morphological and behavioral plasticity. Reports that DNA methylation differs between the queen and worker castes in social insects [1-4] have implied a role for DNA methylation in regulating division of labor. To better understand the function of DNA methylation in social insects, we performed whole-genome bisulfit...
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