introduction: 18f-choline pet-ct is an increasingly used technique in patients with prostate cancer. the main indication is to localise the disease in patients with biochemical recurrence. to accurately interpret 18f-choline pet, knowledge of normal tracer distribution is paramount. the aim of this study was to describe the normal distribution pattern of 18f-choline by measuring the maximum sta...

There exist many bivariate parametric copulas to model data with different dependence features. We propose a new copula family that cannot only handle various patterns appear in the existing families, but also provides more enriched structure. The proposed construction exploits finite mixtures of normal distributions. mixing operation, distinct correlation and mean parameters at each mixture co...

Simultaneous observation of continuous and ordered categorical outcomes for each subject is common in biomedical research but multivariate analysis of the data is complicated by the multiple data types. Here we construct a model for the joint distribution of bivariate continuous and ordinal outcomes by applying the concept of latent variables to a multivariate normal distribution. The approach ...

In this paper, we introduce the Morgenstern type bivariate generalized exponential distribution. This distribution is an extension of Morgenstern type bivariate exponential distribution and the marginal distributions are generalized exponential distribution. We study some properties of this bivariate distribution. Also, some distributional properties of concomitants of order statistics as well ...

The problem of determining if a bivariate normal correlation changes with respect to time or some other covariate is considered. It is assumed that the means and standard deviations of the normal random variables can be consistently estimated from the entire data run, and do not need to be re-estimated for each covariate value. A new estimator of a bivariate normal correlation is given that has...