Noninvasive Assessment of the Biventricular Pacing System Jonathan S. Steinberg, M.D.,∗ Parimal B. Maniar, M.D.,∗ Steven L. Higgins, M.D.,† Sherie L. Whiting, R.N.,† David B. Meyer, M.D.,† Sergio Dubner, M.D.,§ Abrar H. Shah, M.D.,¶ David T. Huang, M.D.,¶ and Leslie A. Saxon, M.D.‡ From the ∗Division of Cardiology and Arrhythmia Service, St. Luke’s–Roosevelt Hospital Center and Columbia Univers...

AIMS Pacing from multiple sites in the left ventricle (LV) may bring about further resynchronization of the diseased heart compared with biventricular (BiV) pacing. We compared acute haemodynamic response (LV dP/dtmax) of multisite and BiV pacing using a quadripolar LV lead. METHODS AND RESULTS In 21 patients receiving cardiac resynchronization therapy, a quadripolar LV lead and conventional ...

With aging of the general population, an increased incidence of conduction disease will result in an increased need for permanent pacemaker therapy. According to the 2015 European Heart Rhythm Association (EHRA) White Book, in the 56 member countries of the European Society of Cardiology (ESC), the pacemaker implantation rate has increased from a mean implantation rate of 614 per million inhabi...

Congestive heart failure (CHF) is a common, debilitating and usually lethal condition responsible for enormous burden on health care. The recent trials have shown improvement in morbidity and mortality with ACE inhibitors and beta blockers1-3. However, despite this the overall prognosis remains dismal. The other alternative of cardiac transplantation has several limitations including the donor ...

BACKGROUND Although there have been few studies in which the hemodynamic effects of right ventricular (RV) and left ventricular (LV) pacing were compared with those of biventricular (BV) pacing, the autonomic changes during these different pacing modes remain unknown. We hypothesized that BV pacing results in improved hemodynamics and a decrease in sympathetic nerve activity (SNA) compared with...

Complications related to coronary sinus lead are not infrequent in recipients of cardiac resynchronization devices. We describe the case of a patient with a biventricular implantable cardioverter defibrillator with persistent phrenic nerve stimulation, previous coronary sinus lead fracture, and severe left subclavian vein stenosis. The reimplantation of a new coronary sinus lead on the left sid...

With aging of the general population, an increased incidence of conduction disease will result in an increased need for permanent pacemaker therapy. According to the 2015 European Heart Rhythm Association (EHRA) White Book, in the 56 member countries of the European Society of Cardiology (ESC), the pacemaker implantation rate has increased from a mean implantation rate of 614 per million inhabi...

OBJECTIVE To analyze the conventional biventricular pacing (BV) and the bifocal (BF) right ventricular (RV) pacing, and to perform a comparative analysis of these two techniques in relation to clinical, functional and echocardiographic parameters in a population without the exclusion criteria of the major studies. METHODS A prospective non-randomized analysis of 36 patients undergoing surgery...

Cardiac resynchronization therapy (CRT), with or without defibrillation, has revolutionized the treatment of heart failure, leading to reverse remodeling (the main prognostic factor in heart failure) and improvements in quality of life, functional class, hospitalizations for heart failure and mortality. However, since CRT was introduced, the proportion of patients who do not respond to the ther...