The progressive rise in multidrug-resistant (MDR) bacterial strains poses serious problems in the treatment of infectious diseases. While the number of newly developed antimicrobial compounds has greatly fallen, the resistance of pathogens against commonly prescribed drugs is further increasing. This rise in resistance illustrates the need for developing novel therapeutic and preventive antimic...

After the beginning of metal processing at the transition from the Neolithic to the Bronze Age, further knowledge of ore mining and smelting had spread from the Near East to central Europe. In the copper ore deposits of Schwaz, in the central part of the Alps, the oldest traces of copper mining derive from the early to middle Bronze Ages. Investigation of a middle to late Bronze Age (1410–920 c...

Nigella sativa L. is a significant medicinal and aromatic plant due to the usage of both its seed fixed oil. The aim study investigate effects on yield, various yield components, essential oil content, chemical composition (2018 year) black cumin when harvesting at four different stages maturity. These were 25% (SH1), 50% (SH2), 75% (SH3) 100% (SH4) browning capsules. Two-year field experiments...

Paracetamol (APAP-Acetaminophen) has been used extensively as antipyretic drug. The purpose of this study was to evaluate the ameliorative role of silymarin or/and Nigella sativa extract against APAP-induced hyperlipidemia in male mice at the biochemical, levels. The mice were divided into seven groups (10/group). The first group was served as control. While, the second group was treated with d...

PURPOSE The aim of this study was to determine the toxic effect of Nigella sativa powder on the liver function which was evaluated by measuring liver enzymes and through histopathological examination of liver tissue. METHODS Twenty four male Sprague Dawley rats were allotted randomly to four groups including: control (taking normal diet); low dose (supplemented with 0.01 g/kg/day Nigella sati...

The present study was conducted to find out the antibacterial activity of aqueous and organic extracts of Nigella sativa (L.) seeds against various bacterial pathogens, namely; S. aureus, P. aeruginosa and E. coli. Plant extract along with different elicitors such as metal ions and commercial drugs was also screened to see the change in efficacy and potency of the compounds. Among different ext...

BACKGROUND Several compounds obtained from plants have potential insecticidal, growth deterrent or repellent characteristics. The control of hard ticks by non-chemical substances was targeted in this study. METHODS The effect of 36 materials on in-vitro ticks was studied, including 2 absolute controls (water only or absolute ethyl alcohol only), 6 conventionally used spinosad preparations (aq...

In Sudan, sickle cell anemia (SCA) is one of the most common inherited disorders hemoglobin that has complications and becomes world problem. Nigella sativa NS (black seed) been reported to have calcium antagonist antioxidant activities, both which play a role in management anemia. The aim current study was evaluate anti-sickling activity extracts, forty patients with were recruited for study. ...

This study was conducted to investigate the effects of dietary black cumin (Nigella sativa L.) oil on growth performance, hemato-biochemical, and histopathology cypermethrin-intoxicated Nile tilapia. After determining LC50 (96 h) value cypermethrin, cypermethrin added water at a ratio 1:20 this concentration, fish were fed for 42 days. To reduce 1% feed as potential protectant. Growth parameter...

The chemical composition of the extracted fixed oil (total fatty acid composition) and volatile oil of Nigella sativa L. seeds grown in Iran were determined by GC and GC/MS. Eight fatty acids (99.5%) and thirty-two compounds (86.7%) have been identified in the fixed and volatile oils, respectively. The main fatty acids of the fixed oil were linoleic acid (55.6%), oleic acid (23.4%), and palmiti...