Background: Protective immune responses induced in the majority of people infected with Mycobacterium tuberculosis enable them to control TB infection. Objective: The aim of this study was to investigate CD56 and CD16 positive peripheral blood mononu-clear cells (PBMCs) and leukocyte subsets from multi-drug resistant pulmonary tuber-culosis (MDR-TB), and compare them with nonresistant (NR) TB p...

background: protective immune responses induced in the majority of people infected with mycobacterium tuberculosis enable them to control tb infection. objective: the aim of this study was to investigate cd56 and cd16 positive peripheral blood mononu-clear cells (pbmcs) and leukocyte subsets from multi-drug resistant pulmonary tuber-culosis (mdr-tb), and compare them with nonresistant (nr) tb p...

Dystrophic epidermolysis bullosa (DEB) is an inheritable blistering disease caused by mutations in COL7A1, which encodes type VII collagen. To address the issue of genotype-phenotype correlations DEB, analyzing consequences COL7A1 using mRNA indispensable. Herein we established a novel method for testing effect DEB extracted from peripheral blood mononuclear cells (PBMCs). We investigated four ...

Vasculogenesis, the in-situ assembly of angioblast or endothelial progenitor cells (EPCs), may persist into adult life, contributing to new blood vessel formation. However, EPCs are scattered throughout newly developed blood vessels and cannot be solely responsible for vascularization. Here, we identify an endothelial progenitor/stem-like population located at the inner surface of preexisting b...

background: blood is permanently exposed to oxidation stress and therefore has a high antioxidants capacity. many different factors increasing the demand for the antioxidant capacity can be observed in the stored blood of donors. consequently, damage to erythrocytes by free radicals may occur. so it is useful to control the alternation of anti-oxidant enzymes in stored blood at different days o...

a simple inexpensive con!nuous quality control method, by means of eight basic blood coun!ng parameters, obtained from automated hematology analyzers, using pa!ent samples, is described. a few samples with low, normal and high values were selected and introduced to the instrument early in the morning as the first count, the results of which are plo#ed on the appropriate chart as dots. the same ...

Abstract The complex nature of the immune system requires deep interrogation at single-cell level. Flow cytometry using CyTOF® technology employs antibodies tagged with isotopically enriched metals instead fluorophores, resulting in discrete signals that facilitate highly multiparametric characterization on a CyTOF enables analysis over 50 parameters simultaneously without impediments spectral ...

UNLABELLED Enhancing antiviral host defense responses through nutritional supplementation would be an attractive strategy in the fight against influenza. Using inoculation with live attenuated influenza virus (LAIV) as an infection model, we have recently shown that ingestion of sulforaphane-containing broccoli sprout homogenates (BSH) reduces markers of viral load in the nose. To investigate t...