نتایج جستجو برای: blood vessel diseases
تعداد نتایج: 1436879 فیلتر نتایج به سال:
AIM To investigate a potential difference in ocular vascular reactivity during carbogen breathing in optic nerve head, choroid, and retina between healthy smokers and non-smokers. METHODS 25 (13 smokers and 12 non-smokers) healthy male volunteers participated in this observer masked, two cohort study. During inhalation of carbogen (5% CO(2) and 95% O(2)) over 10 minutes measurements were take...
Is breakdown of the blood-brain barrier responsible for lacunar stroke, leukoaraiosis, and dementia?
BACKGROUND The pathogenesis of and relationship between small deep (lacunar) infarcts, cerebral white matter disease (leukoaraiosis or white matter hyperintensities), and progressive cognitive impairment or dementia are much debated. SUMMARY OF COMMENT We hypothesize that cerebral small-vessel endothelial (ie, blood-brain barrier) dysfunction, with leakage of plasma components into the vessel...
Aim: To investigate a potential difference in ocular vascular reactivity during carbogen breathing in optic nerve head, choroid, and retina between healthy smokers and nonsmokers. Methods: 25 (13 smokers and 12 non-smokers) healthy male volunteers participated in this observer masked, two cohort study. During inhalation of carbogen (5% CO2 and 95% O2) over 10 minutes measurements were taken usi...
The study of the coronary vessel structure is crucial to the diagnosis of atherosclerosis and other cardiovascular diseases, which together account for ∼ 35% of all deaths in the United States per year. Vessel Segmentation from CTA data is challenging because of non-uniform image intensity along the vessel, and the branching and thinning geometry of the vessel tree. We present a novel method fo...
Angiogenesis is tightly associated with the outgrowth of adipose tissue, leading to obesity, which is a risk factor for type 2 diabetes and hypertension, mainly because expanding adipose tissue requires an increased nutrient supply from blood vessels. Therefore, induction of vessel abnormality by adipokines has been well-studied, whereas how altered vascular function promotes obesity is relativ...
Arteriogenesis requires growth of pre-existing arteriolar collateral networks and determines clinical outcome in arterial occlusive diseases. Factors responsible for the development of arteriolar collateral networks are poorly understood. The Notch ligand Delta-like 4 (Dll4) promotes arterial differentiation and restricts vessel branching. We hypothesized that Dll4 may act as a genetic determin...
Methylmercury [MeHg] has long been known as a neurotoxic agent. Recent epidemiological research has also linked MeHg exposure to cardiovascular disease. However, the precise mechanisms linking MeHg toxicity to blood vessels at the cellular levels are lacking. Endothelial cells exist as a single monolayer of cells that form the inner lining of blood vessels and are crucial to the structure and f...
this research was conducted to examine the effect of a concurrent training on rest level of leptin of plasma and some hormonal factors in non-athlete subjects. the research population included non-athlete men who didn’t participate in any organized sport activities. 30 men were chosen voluntarily among the above-mentioned population and were divided into 2 groups: experimental (15 subjects) an...
Angiogenic therapy, which involves the use of an exogenous stimulus to promote blood vessel growth, is an attractive approach for the treatment of ischemic diseases. It has been shown in animal models that the stimulation of blood vessel growth leads to the growth of the whole vascular tree, improvement of ischemic tissue perfusion and improved muscle aerobic energy metabolism. However, very fe...
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