نتایج جستجو برای: bmp7
تعداد نتایج: 600 فیلتر نتایج به سال:
The authors noted that a reference regarding the suppressive effect of BMP7 on EMT and bone metastasis in prostate cancer was inadvertently omitted. The authors have added the following publication to the references: a putative regulator of epithelial homeostasis in the human prostate, is a potent inhibitor of prostate cancer bone metastasis in vivo. Am. The html and pdf versions of this articl...
Ventral midline cells at different rostrocaudal levels of the central nervous system exhibit distinct properties but share the ability to pattern the dorsoventral axis of the neural tube. We show here that ventral midline cells acquire distinct identities in response to the different signaling activities of underlying mesoderm. Signals from prechordal mesoderm control the differentiation of ros...
The Rit GTPase is widely expressed in developing and adult nervous systems, and our previous data with pheochromocytoma cells implicate Rit signaling in NGF-induced neurite outgrowth. In this study, we investigated a role for Rit in neuronal morphogenesis. Expression of a dominant-negative (dn) Rit mutant in hippocampal neurons inhibited axonal growth but potentiated dendritic growth. Conversel...
PURPOSE Bone morphogenetic proteins (BMPs) are multi-functional cytokines that have wide ranging effects on a variety of cells and tissues. In the present study, we profile the expression of BMPs, BMP receptors, and BMP associated proteins in the human trabecular meshwork (TM) and optic nerve head (ONH), two tissues involved in glaucoma pathogenesis. METHODS Total RNA was isolated and subject...
The bone morphogenetic protein (BMP) expression in vertebrates suggests a reiterative function of these molecules during eye development. However, genetic analysis in mice has provided only partial information. Using the chick embryo as a model system, we have analyzed possible additional functions of BMP4 during optic cup formation. Here we describe the expression pattern of Bmp4 and Bmp7 and ...
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