There is ample evidence identifying lead, methylmercury, and polychlorinated biphenyls (PCBs) as neurotoxic agents. A large body of data on the neurotoxicity of lead, based on both epidemiologic studies in children and animal models of developmental exposure, reveals that body burdens of lead typical of people in industrialized environments produce behavioral impairment. Methylmercury was ident...

INTRODUCTION Despite the growing body of literature on the consequences of providing non-professional care to stroke survivors, the determinants of caregiving burden are still not fully recognized. Identification of significant determinants can facilitate caregiver intervention programs. The aim of this study was to evaluate the level of burden borne by caregivers of stroke patients and to iden...

To determine the current risk of internal radiation exposure after the Chernobyl accident, the (137)Cs body burden of the inhabitants of Bryansk Oblast, Russian Federation was evaluated, from 1998 to 2008. The study population is composed of 84 666 people who visited Bryansk No. 2 Hospital. A whole-body counter was used for measurement of (137)Cs body burden. (137)Cs concentration was significa...

BACKGROUND Whole body cardiovascular MR (WB CVMR) combines whole body angiography and cardiac MR assessment. It is accepted that there is a high disease burden in patients with diabetes, however the quantification of the whole body atheroma burden in both arterial and cardiac disease has not been previously reported. In this study we compare the quantified atheroma burden in those individuals w...

BACKGROUND Men commence dialysis with a higher estimated glomerular filtration rate (eGFR) than women and are more likely to transition from chronic kidney disease (CKD) to end-stage renal disease. We hypothesized that for a given estimated body surface area (BSA) men have a greater metabolic burden, and that consequently, the practice of indexing GFR to BSA results in gender differences in the...

AIMS Obesity causes a high disease burden in Australia and across the world. We aimed to analyse the cost-effectiveness of weight reduction with pharmacotherapy in Australia, and to assess its potential to reduce the disease burden due to excess body weight. METHODS We constructed a multi-state life-table based Markov model in Excel in which body weight influences the incidence of stroke, isc...

this commentary to the editorial of hajizadeh argues that the economic, social and health consequences of legalizing cannabis in canada will depend in large part on the exact stipulations (mainly from the federal government) and on the implementation, regulation and practice of the legalization act (on provincial and municipal levels). a strict regulatory framework is necessary to minimize the ...

background: sick leave from work due to psychiatric disorders is a major public health problem, not only in japan but also worldwide. as males and females in japan tend to differ in their approach to work, a gender difference in perfectionism might be expected. we investigated the background factors leading to long-term absence from work due to sickness among psychiatric outpatients in japan . ...

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background: the general pattern of epidemiologic transition from communicable to non-communicable diseases is also observed for gastrointestinal and liver diseases (gild), which constitute a heterogeneous array of causes of death and disability. we aimed to describe the trend of gild in iran based on the global burden of disease (gbd2010) study from 1990 to 2010. methods: the trend of number of...