Bolus calculators are effective tools in controlling blood glucose levels in patients treated with insulin. Diabetics is a new software devised for patients to facilitate and improve self-managing for prandial insulin dosing and for better controlling food intake. This device contains two integral parts: a nutrition database and a bolus calculator. The algorithm is based on a formula in which c...

Objective: Meal management in Type 1 Diabetes (T1D) has barriers such as miscalculation of doses, insufficient carbohydrate counting and numeracy skills. “My Friend Carbohydrate Bolus Calculator” mobile app was developed a hybrid version nutrition apps insulin titration to calculate meal’s carbs the matching bolus dose. This study investigates facilitator role on lives people with T1D. Material...

A total of 295 goats from 4 breeds (Alpine, n = 74; Angora, n = 75; Boer-cross, n = 73; Spanish, n = 73) were used to assess the retention of 3 types of electronic ruminal boluses (B1, 20 g, n = 95; B2, 75 g, n = 100; and B3, 82 g, n = 100) according to breed and feeding conditions. Time for bolus administration, reading with a handheld reader, and animal data recording (goat identification, br...

BACKGROUND The role of fluid resuscitation in the treatment of children with shock and life-threatening infections who live in resource-limited settings is not established. METHODS We randomly assigned children with severe febrile illness and impaired perfusion to receive boluses of 20 to 40 ml of 5% albumin solution (albumin-bolus group) or 0.9% saline solution (saline-bolus group) per kilog...

BACKGROUND Swallowing is triggered when a food bolus being prepared by mastication has reached a defined state. However, although this view is consensual and well supported, the physical properties of the swallowable bolus have been under-researched. We tested the hypothesis that measuring bolus physical changes during the masticatory sequence to deglutition would reveal the bolus properties po...

BACKGROUND There have been results showing the influence of bolus viscosities and consistency on esophageal motility and transit. However, there is no description about the influence of two different viscous boluses on esophageal contractions, bolus transit and perception of transit. Our objective in this investigation was to evaluate the esophageal transit and contraction after swallows of two...

Aerosol bolus dispersion is a physiological test of lungs, which uses monodisperse submicron particles to measure intrapulmonary convective gas mixing. In this study, aerosol bolus dispersion was measured in healthy subjects in order to assess reference values for possible clinical applications, to assess the reproducibility of these values, and to identify physical and physiological factors in...

We previously demonstrated that sustained depletion of methylguanine DNA methyltransferase (MGMT) activity is required for optimal reversal of chloroethylnitrosourea resistance in tumor cells. The purpose of this study was to design O(6)-benzylguanine (BG) treatments that deplete MGMT activity in tumor cells and xenograft tumors in a prolonged manner. When SF767 cells were treated with a bolus ...