Methods Both the dual-sequence CMR perfusion technique [1] and the dual-bolus protocol [2] were performed in five canines and 35 clinical subjects using a 1.5 Tesla scanner. Gd-DTPA at 0.005 mmol/kg and 0.05 mmol/kg were administered during separate breath holds. Typical imaging parameters: 1 RR, 90° saturation pulse, 50°read out angle, saturation recovery 90 ms, TR 2.4 ms, TE 1.2 ms, matrix si...

When the planning target volume (PTV), extends close to or beyond the skin, inverse-planned intensity-modulated radiotherapy can boost the fluence from tan- gential angles to superficial parts of the PTV due to the buildup effect. This can result in significant regions of high dose upon a small movement in the patient's position. We analyzed different methods of reducing this effect in the Tomo...

PURPOSE To compare fully quantitative and semiquantitative analysis of rest and stress myocardial blood flow (MBF) and myocardial perfusion reserve (MPR) using a dual-bolus first-pass perfusion MRI method in humans. MATERIALS AND METHODS Rest and dipyridamole stress perfusion imaging was performed on 10 healthy humans by administering gadolinium contrast using a dual-bolus protocol. Ventricul...

OBJECTIVE Boluses are used in high-energy radiotherapy in order to overcome the skin sparing effect. In practice though, commonly used flat boluses fail to make a perfect contact with the irregular surface of the patient's skin, resulting in air gaps. Hence, we fabricated a customized bolus using a 3-dimensional (3D) printer and evaluated its feasibility for radiotherapy. METHODS We designed ...

OBJECTIVES The aim of this study was to compare the image quality, the degree of artifacts and the percentage of timing of the optimal hepatic arterial phase (HAP) between test-bolus and bolus-tracking methods on gadolinium-ethoxybenzyl-diethylenetriamine pentaacetic acid (Gd-EOB-DTPA)-enhanced magnetic resonance imaging (MRI). METHODS In this prospective study, 60 patients who underwent 3-di...

Brass mesh bolus has been shown to be an acceptable substitute for tissue-equivalent bolus to increase superficial dose for chest wall tangent photon radiotherapy. This work investigated the increase in surface dose, the change in the dose at depth, and the safety implications of higher energy photon beams when using brass mesh bolus for postmastectomy chest wall radiotherapy. A photon tangent ...