BACKGROUND A theoretical model and an experimental setup were specifically designed to identify and determine the delay of the cortical bone response (restricted to mineralization and demineralization) to a stress change. METHODS The in vivo experiment considered two groups of rats: a running group and a control sedentary group. The running group rats were compelled to a running activity for ...

UNLABELLED Calcium metabolism of the mother is modified during pregnancy because of the mineralization of the fetus skeleton. OBJECTIVE To evaluate the association of calcium intake and bone demineralization during pregnancy. MATERIAL AND METHODS At each trimester of pregnancy a validated food frequency intake questionnaire was administered to assess individual daily calcium intake in a coh...

Osteogenesis imperfecta is a genetically determined pathology that implies bone variability and osteoporosis with early onset of fractures after low energy trauma. For a better understanding of the clinical problems, Sillence and Danks created a classification. The study group consisted of 12 patients both males and females, with ages ranging from 2 years and 3 months to 12 years. All of them c...

Bone and calcium metabolism abnormalities, mainly resulting in osteopoenia and osteoporosis, have long been recognized as a complication of untreated coeliac disease (CD). It has also been reported that, in adults, skeletal disorders may be the only presenting feature of a gluten-sensitive enteropathy (1–3) . The recent availability of simple and reliable biohumoral and instrumental investigati...

Correspondence: Dr. Pierangelo Spedini, Divisione di Medicina II, sezione di Ematologia, Istituti Ospitalieri di Cremona, viale Concordia 1, 26100 Cremona, Italy. A71-year old man was referred to our hospital because of osteolysis of the right femur. Two weeks before admission he had developed pain, swelling and functio laesa of his right hip. Bone biopsy showed a lymphoid infiltrate, not furth...

The inorganic part of hard tissues (bones and teeth) of mammals consists of calcium phosphate, mainly of apatitic structure. Similarly, most undesired calcifications (i.e. those appearing as a result of various diseases) of mammals also contain calcium phosphate. For example, atherosclerosis results in blood-vessel blockage caused by a solid composite of cholesterol with calcium phosphate. Dent...

Endochondral bone formation was induced in postnatal rats by implantation of demineralized rat bone matrix. Corresponding control tissue was generated by implanting inactive extracted bone matrix, which did not induce bone formation. At various times, implants were removed and sequentially extracted with guanidine hydrochloride, and then EDTA and guanidine hydrochloride. Transforming growth fac...

Extracted human teeth are frequently used for research or educational purposes. Therefore, it is necessary to store them in disinfectant solutions that do not alter dental structures. Thus, this study evaluated the influence of storage solution on enamel demineralization. For that purpose, sixty samples were divided into the following groups: enamel stored in formaldehyde (F1), stored in thymol...

In the present study, the demineralizing ability of BioPure MTAD (Dentsply/Tulsa, Tulsa, OK), 17% EDTA, and 5% citric acid on radicular dentin was quantitatively and longitudinally analyzed. 3 mm thick disks were obtained at the root cervical third from 9 maxillary human molars, and a standardized smear layer was produced. Cosite images of the dentin surface were obtained after several cumulati...