نتایج جستجو برای: bone sialoprotein

تعداد نتایج: 305372  

Journal: :Journal of cell science 2003
Fina Liu Luc Malaval Jane E Aubin

Mesenchymal stem cells give rise to osteoprogenitors that proliferate and differentiate into identifiable preosteoblasts, osteoblasts, bone lining cells and osteocytes. To identify and establish a molecular profile for the more primitive and uncharacterized cells in the lineage, relatively rare (<1%) osteoprogenitors present in primary cultures of fetal rat calvaria cell populations were identi...

Journal: :Bone 2015
B L Foster M Ao C Willoughby Y Soenjaya E Holm L Lukashova A B Tran H F Wimer P M Zerfas F H Nociti K R Kantovitz B D Quan E D Sone H A Goldberg M J Somerman

Bone sialoprotein (BSP) is a multifunctional extracellular matrix protein found in mineralized tissues, including bone, cartilage, tooth root cementum (both acellular and cellular types), and dentin. In order to define the role BSP plays in the process of biomineralization of these tissues, we analyzed cementogenesis, dentinogenesis, and osteogenesis (intramembranous and endochondral) in cranio...

Journal: :Genetics and molecular research : GMR 2016
R J Wei T Y Li X C Yang N Jia X L Yang H B Song

Bone metastasis is a common complication in prostate cancer patients that can cause bone pain and pathological fracture. This study tested serum levels of prostate specific antigen (PSA), alkaline phosphatase (ALP), bone sialoprotein (BSP), collagen type I pyridine crosslinking peptide (ICTP) in prostate cancer patients and the significance of the receiver operator characteristic (ROC) curve in...

2014
Insun Song Kabsun Kim Jung Ha Kim Young-Kyoung Lee Hyun-Jung Jung Hae-Ok Byun Gyesoon Yoon Nacksung Kim

Osteoblasts are specialized mesenchymal cells that are responsible for bone formation. In this study, we examine the role of GATA4 in osteoblast differentiation. GATA4 was abundantly expressed in preosteoblast cells and gradually down-regulated during osteoblast differentiation. Overexpression of GATA4 in osteoblastic cells inhibited alkaline phosphatase activity and nodule formation in osteoge...

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