TOPIC: Pharmacotherapeutics TYPE: Medical Student/Resident Case Reports INTRODUCTION: Carbapenem is a bactericidal antibiotic against gram positive, negative, and anaerobic bacteria. Its use has increased in the recent years due to increasing prevalence of extended spectrum beta lactamase (ESBL) resistant bacteria (1). It important recognize its reversible neurotoxic side effect. Neurotoxicity ...

A 60-year-old man presented to his general practitioner with complaints of indigestion and flu-like symptoms. The results of a clinical examination were unremarkable. The only abnormality found in routine hematology and biochemistry investigations was an increased serum alkaline phosphatase concentration (131 U/L; reference interval, 35–120 U/L). Given his abdominal discomfort, the patient was ...

BACKGROUND Intraductal papillary mucinous neoplasm (IPMN) is a rare tumor that originates in the pancreatic duct. The diagnosis of benign, borderline or malignant to IPMN is significant in terms of making an appropriate treatment plan and prognosis. This article summarizes our clinical experience of a case report and discussion by literature review. Methods and case report: A 73 year old male p...

Purpose TWIST is a critical factor for predicting prognosis in several human cancers. Here, we study the prognostic significance of TWIST1 and TWIST2 in Head and Neck squamous cell carcinoma (HNSCC) as well as interactions of TWISTs with both gender and smoking in patient survival. Methods upper quartile normalized RNA-seq V2 RSEM values of TWIST1 and TWIST2 expressions were retrieved from a ...