نتایج جستجو برای: boron neutron capture therapy

تعداد نتایج: 829590  

Journal: :iranian journal of medical physics 0
mona zolfaghari department of physics, faculty of science, k. n. t university of technology, tehran, iran mahmood sedaghatizadeh department of physics, faculty of science, k. n. t university of technology, tehran, iran

introduction electron linear accelerator (linac) can be used for neutron production in boron neutron capture therapy (bnct). bnct is an external radiotherapeutic method for the treatment of some cancers. in this study, varian 2300 c/d linac was simulated as an electron accelerator-based photoneutron source to provide a suitable neutron flux for bnct. materials and methods photoneutron sources w...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 1998
L Guan L A Wims R R Kane M B Smuckler S L Morrison M F Hawthorne

The application of immunoprotein-based targeting strategies to the boron neutron-capture therapy of cancer poses an exceptional challenge, because viable boron neutron-capture therapy by this method will require the efficient delivery of 10(3) boron-10 atoms by each antigen-binding protein. Our recent investigations in this area have been focused on the development of efficient methods for the ...

2003
Grzegorz Tracz Ludwik Dąbkowski Dominik Dworak Krzysztof Pytel Urszula Woźnicka

Boron Neutron Capture Therapy (BNCT) [4, 5] is a form of a radiation therapy used for treatment of some kinds of cancer (mainly glioblastoma multiforme) which, due to their character, are hard to be extracted with surgical methods. The BNCT method involves the delivery of a capture compound − the B isotope is usually used – which preferentially concentrates in the cancer tissue, followed by the...

Alireza Sadremomtaz, Peyvand Taherparvar Sepideh Gholami

Introduction: Neutrons have many applications in various fields, such as medicine. The important application of neutron in medical science is in Boron Neutron Capture Therapy (BNCT). Because of this, determination of neutron dose and flux is critical for the health maintaining of workers and patients exposed to this beam. The neutron radioisotope sources produce gamma rays in ...

2014
Tanja Schaffran Nan Jiang Markus Bergmann Ekkehard Küstermann Regine Süss Rolf Schubert Franz M Wagner Doaa Awad Detlef Gabel

The potential of boron-containing lipids with three different structures, which were intended for use in boron neutron capture therapy, was investigated. All three types of boron lipids contained the anionic dodecaborate cluster as the headgroup. Their effects on two different tumor models in mice following intravenous injection were tested; for this, liposomes with boron lipid, distearoyl phos...

D.V. Bandekas, E. Saitioti, J.G. Fantidis, N. Vordos,

Background: Boron Neutron Capture Therapy (BNCT) is a very promising treatment for patients suffering gliobastoma multiforme, an aggressive type of brain cancer, where conventional radiation therapies fail. Thermal neutrons are suitable for the direct treatment of cancers which are located at near-tissue-surface deep-seated tumors need harder, epithermal neutron energy spectra. Materials and Me...

ژورنال: سنجش و ایمنی پرتو 2019

In the recent years some studies has been done to consider the capability of Tehran Research Reactor for Boron neutron capture therapy (BNCT). The purpose of this study is to evaluate the sensitive organs dose during the treatment of patient with deep brain tumor by TRR. The calculation has been carried out using the Monte Carlo code MCNPX for ZUBAL head and neck phantom. The method was tested ...

ژورنال: سنجش و ایمنی پرتو 2015

In Boron Neutron Capture Therapy (BNCT), the patient is injected with a tumor localizing drug containing a boron-10 compound. Then the tumor region is irradiated with an appropriate neutron beam. Lethal dose deposited by 10B (n, α)7Li reaction products cause destruction of the tumor cell. Recently, a lot of efforts have been done for the use of Tehran Research Reactor (TRR) for BNCT and a...

2012
Gianni Ciofani Serena Danti Giada Graziana Genchi Delfo D’Alessandro Jean-Luc Pellequer Michaël Odorico Virgilio Mattoli Mario Giorgi

Boron nitride nanotubes (BNNTs) have attracted huge attention in many different research fields thanks to their outstanding chemical and physical properties. During recent years, our group has pioneered the use of BNNTs for biomedical applications, first of all assessing their in vitro cytocompatibility on many different cell lines. At this point, in vivo investigations are necessary before pro...

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید