pneumonia is the leading cause of mortality in young children worldwide. early diagnosis and empiric antibacterial therapy is an important strategy to improve outcome. the world health organization (who) has developed case management guidelines to reduce pneumonia-related deaths through early diagnosis and antibiotic treatment. for management purpose, pneumonia is subclassified by its severity....

introduction: foot-and-mouth disease (fmd) is a highly contagious and economically devastating viral disease of livestock that is categorized in list a of animal diseases by the world organisation for animal health (oie). vaccination is effective against fmd and the vaccine production centers largely use the industrial ultra-filtration and chromatography in order to remove the cellular proteins...

Bovine respiratory disease (BRD) is a multifaceted syndrome involving physiological stress, commingling, and several viral and bacterial pathogens. Physiological alterations in response to individual stressors such as weaning, transportation, castration and commingling have been observed; however, high-risk, newly received stocker cattle are often subjected to these stressors concurrently. Wher...

Bovine herpes virus 1 (BHV-1) is primarily associated with clinical syndromes such as rhinotracheitis, pustular vulvovaginitis and balanoposthitis, abortion, infertility, conjunctivitis and encephalitis in bovine species. The main sources of infection are the nasal exudates and the respiratory droplets, genital secretions, semen, fetal fluids and tissues. The BHV-1 virus can become latent follo...

A combination vaccine (Bovi-Shield FP4 + L5, Pfizer Animal Health) containing modified-live virus (MLV) components against bovine herpesvirus-1 (BHV-1), bovine viral diarrhea virus BVDV), parainfluenza virus-3 (PI3), bovine respiratory syncytial virus (BRSV), and inactivated cultures of Leptospira canicola, grippotyphosa, hardjo, icterohaemorrhagiae, and pomona was evaluated for safety in pregn...

Summary studies of dairy cow removal indicate increasing levels of mortality over the past several decades. This poses a serious problem for the US dairy industry. The objective of this project was to evaluate associations between facilities, herd management practices, disease occurrence and death rates on US dairy operations through an analysis of the National Animal Health Monitoring System's...

The prevalence of bovine respiratory disease complex (BRDC) has remained unchanged for decades despite efforts to suppress the disease through prevention programs aimed at vaccination and metaphylaxis. An additional approach that focuses on host response to infection by the pathogens responsible for BRDC, through the selection of animals that are less susceptible to the disease, has been undert...