the male breast cancer (mbc) is a very rare neoplasm which accounts for 0.5-1% of the total cases of breast cancer. bilateral involvement is reported to occur in fewer than 2% of all the diagnosed cases of mbc, and synchronous tumors are very rare. because of its rarity, little is known about mbc etiology, its clinical findings and treatment. most patients present with a painless breast mass. t...

objective(s):leptin receptor (lepr) is a member of the class i cytokine receptor super-family that is known implicated in the initiation and progression of breast cancer. we have investigated the effect of q223r polymorphism on the breast cancer susceptibly in a sample of iranian subjects. materials and methods:we utilized a polymerase chain reaction (pcr) restriction fragment length polymorphi...

background post-mastectomy breast reconstruction is commonly performed in the united states with numerous options available to patients and providers. this study evaluated patient race and provider in prediction of patient satisfaction following post-mastectomy breast reconstruction. methods the patient satisfaction for women who underwent post mastectomy breast reconstruction at university of ...

background: brca1 and brca2 genes have been recognized to be responsible for 20-30% of hereditary breast can­cers and approximately 50% of familial breast and ovarian cancers. therefore, the demand for brca1 and brca2 muta­tion screening is rapidly increasing as their identification will affect medical management of people at increased risk. because of high costs involved in analysis of brca1 a...

Aim of this study is to show that ipsilateral breast tumor recurrence (IBTR) after breast conserving surgery can be reduced by proper surgery and modern radiotherapy techniques. Three hundred and seventy eight women with stage I or II breast cancer had breast conserving surgery and received 51-56.1 Gy of postoperative radiation to the whole breast in 1.7 Gy fractions, but patients received diff...

introduction: the adaptive neuro-fuzzy inference system (anfis) is a soft computing model based on neural network precision and fuzzy decision-making advantages, which can highly facilitate diagnostic modeling. in this study we used this model in breast cancer detection. methodology: a set of 1,508 records on cancerous and non-cancerous participant’s risk factors was used.  first, the risk fact...

conclusions expression of armc3 in tumor samples and normal adjacent tissue is very important. the expression of this gene in tumor-adjacent tissue may be associated with the stage of cancer; it may be that these tissues are affected by epigenetic and oncogenic changes of breast cancer. accordingly, aberrant expression of armc3 in tumor samples may be an attractive candidate for use as a tumor ...