Breast cancer mortality is principally due to recurrent tumors that arise from a reservoir of residual tumor cells that survive therapy. Remarkably, breast cancers can recur after extended periods of clinical remission, implying that at least some residual tumor cells pass through a dormant phase prior to relapse. Nevertheless, the mechanisms that contribute to breast cancer recurrence are poor...

Background: Breast cancer-related adversity can result in severe psychological issues. However, some patients were able to demonstrate resilience, while others not. Therefore, the concept of resilience breast cancer requires further clarification.Purpose: This study aimed systematically analyze with cancer, its attributes, antecedents, consequences, and empirical referents.Methods: analysis use...

Breast cancer is a leading cause of death among women worldwide due to therapeutic resistance and cancer recurrence. Cancer stem cells are believed to be responsible for resistance and recurrence. Many efforts to overcome resistance and recurrence by regulating cancer stem cells are ongoing. Bub1 (Budding uninhibited by benzimidazoles 1) is a mitotic checkpoint serine/threonine kinase that play...

Breast cancer is the leading cause of death affecting women worldwide, according to mortality estimation and incidence. In Chile, breast cancer ranks third among cancer mortality rates. Two-hundred and eighty-three breast cancer patients registered at the Gustavo Fricke Hospital of Viña del Mar, Chile, were studied to assess the influence of several factors on the recurrence and survival of bre...

BACKGROUND Breast cancer will affect one in 12 Australian women in their lifetime. After potentially curative treatment, it is usual for patients to be followed up for many years. However, controversies surround follow up, and its value is uncertain. AIM This study reviews the evidence and describes the role of routine follow up in the management of breast cancer in a tertiary hospital. By es...

the present research is a field study in order to investigate scale and ways of doing breast self examination (bse). 270 nurses employed by the medical sciences university’s hospitals related to the ministry of health, and medical education in city of tehran are selected and involved in research on the basis of simple random sampling. the data collection tool was a protrayed questionnaire which...

Abstract Background The aim of this study was to investigate whether the PAM-50-based 46-gene assay carries prognostic value for risk local recurrence breast cancer. Methods Austrian Breast and Colorectal Cancer Study Group (ABCSG) 8 RCT compared 5 years tamoxifen with 2 followed by anastrozole 3 in postmenopausal women endocrine receptor-positive This included patients from trial who had breas...

PURPOSE Distant metastasis and recurrence are major prognostic factors associated with breast cancer. Both lymphovascular invasion (LVI) and blood vessel invasion (BVI) are important routes for metastasis to regional lymph nodes and for systemic metastasis. Despite the importance of vascular invasion as a prognostic factor, application of vascular invasion as a histopathological criterion is co...

Women with early stage breast cancer frequently receive adjuvant chemotherapy to prevent recurrence; however, not all patients benefit. Recently, gene expression marker panels, such as Oncotype DX, that may better predict risk of breast cancer recurrence have become commercially available and are being used to guide treatment decisions. Oncotype DX analyzes the expression of 21 genes within a t...

We evaluated the role of metabolic parameters in the prediction of disease recurrence in operable invasive ductal breast cancer patients treated with neoadjuvant chemotherapy (NAC).We retrospectively evaluated 139 female patients (mean age, 46.5 years; range: 27-72 years) with invasive ductal breast cancer, treated with NAC followed by surgery. All patients underwent F-fluorodeoxyglucose positr...