Cell counting of bronchoalveolar lavage (BAL) fluid is performed manually in routine practice. This has both methodological and inherent errors; however, the accuracy and suitability of automated counting devices have been questioned. In this study, a Coulter Counter D Industrial model was calibrated and then used to measure the total cell count in unprocessed bronchoalveolar lavage fluid, and ...

BACKGROUND HIV is present in bronchoalveolar lavage cells of some but not all HIV seropositive patients. Abnormalities of lung function have been described in such patients in the absence of clinically overt pneumonia or other respiratory infections. It is possible that the presence of HIV in alveolar macrophages could account for these abnormalities. It is also possible that the presence of HI...

BACKGROUND Cytologic examination of specimens obtained from the respiratory tract is a lung cancer diagnostic procedure with high specificity but moderate sensitivity. The use of molecular biomarkers may enhance the sensitivity of cytologic examination in the detection of lung cancer. METHODS Complement factor H, a protein secreted by lung cancer cells, was quantified in a series of bronchoal...

BACKGROUND Multiple sensory neuropeptides are present in human airways and may contribute to diseases such as asthma. This study quantified and characterised substance P (SP), neurokinin A (NKA), and calcitonin gene related peptide (CGRP) immunoreactivity in bronchoalveolar lavage fluid in asthmatic and normal subjects. METHODS Using specific radioimmunoassay (RIA), SP, NKA and CGRP were meas...

metastatic lesions represent 1-8% of all malignant tumors of the mouth and jaws, which are regarded as rare sites of metastases from different primary tumors. metastases in mouth soft tissue are also rare, and within these it is on the gums where they more frequently occur. primary tumors which metastasize to the mouth are most commonly: lung, breast, and kidney. clear cell carcinoma is the mos...


 Purpose: To investigate the action of miR-483-3p in pediatric pneumonia and identify potential biomarkers.
 Methods: Bronchoalveolar lavage was collected from 38 patients 25 healthy children. The expression determined using qRT-PCR. Alveolar macrophages children were cultured used for functional assays. Transwell assay conducted to evaluate macrophage cell migration. Cell viability ...

BACKGROUND Bronchoalveolar lavage is considered a safe procedure. When performed in the mechanically ventilated patient, however, potentially harmful effects on respiratory and haemodynamic functions have been reported in which the size of the bronchoscope may play a part. Two different size bronchoscopes (adult and paediatric) were therefore investigated with regard to bronchoalveolar lavage y...

BACKGROUND While Candida pneumonia is life-threatening, biomarker measurements to early detect suspected Candida pneumonia are lacking. This study compared the diagnostic values of measuring levels of (1, 3)-β-D-glucan in endotracheal aspirate, bronchoalveolar lavage fluid, and serum to detect suspected Candida pneumonia in immunocompromised and critically ill patients. METHODS This prospecti...