Adult cardiovascular disease has its roots in childhood, Various surveys have shown a significant correlation between early atherosclerotic changes indentified at autopsy of children and young adults, and both total cholesterol (TC) and low-density lipoprotein (LDL cholesterol) levels. The hypercholesterolemic neonates time for diagnosis of high risk neonate infants. The aim of this study is to...

We have isolated and partially characterized five populations of lipoproteins from the pool of immunoisolated apoA-I-containing lipoproteins obtained from normal human plasma. The first three populations, each containing apoA-I and apoE, were isolated completely by sequential, selected affinity immunosorption against apoA-I and apoE. The lipoproteins isolated by this strategy fall into three mo...

Many in vitro studies have shown that dietary antioxidants, such as vitamin C (ascorbic acid), vitamin E ( tocopherol), ß-carotene, and flavonoids, act as effective antioxidants in biological systems such as plasma, lipoproteins, and cultured cells (1–3). For example, vitamin C effectively inhibits lipid and protein oxidation in human plasma exposed to various (patho)physiologically relevant ty...

Polycystic ovary syndrome (PCOS) is the most common reproductive-endocrine disorder affecting 10% of women. PCOS increases risk developing diabetes and cardiovascular disease (CVD). We have previously shown high-risk young women with without an atherogenic lipoprotein profile, this exacerbated in PCOS, elevated triglycerides (TG), remnant cholesterol apoB-lipoproteins. The aim study was to dete...

conclusions we found a relatively high value of tc and tg in our study. considering the relationship between high levels of lipids in the neonatal period and coronary artery disease in the adult population, we recommend future cohort studies for this statistical society. results of the 174 neonates, 97 were female. vaginal delivery was recorded in 79.8%. there were no significant differences re...

Cardiovascular diseases with an incidence of approximately 50% are the main causes of death in most advanced countries and an increasing trend in the developing world as well. The World Health Organization estimates that 12 million people per year worldwide die from cardiovascular diseases. Cardiovascular diseases are becoming an increasing problem worldwide and hypercholesterolemia has been co...

The last decade has witnessed an explosion in studies of the role of lipoproteins in brain function. Neurons require a continuous supply of lipids for membrane synthesis and acetylcholine production. Indeed, the brain is a site of intense lipid turnover—even though the central nervous system (CNS) accounts for only 2.1% of body weight, it contains 23% of total body cholesterol.1 Lipid metabolis...

100 patients with beta-thalassemia trait, comprised of 55 men and 45 women, participated in a study to measure serum lipoproteins. the results were compared with the data obtained from 100 control subjects of the same age and sex. a significantly lower level of mean serum total cholesterol and ldl cholesterol, and a much higher level of hdl cholesterol were obtained in beta-thalassemia trait as...