C-reactive protein (CRP) from the American horseshoe crab, Limulus polyphemus, exhibits complex membrane activities. Here, we describe the behavior of protein and lipid as CRP interacts with model liposomes and bacterial membranes. Limulus C-reactive protein (L-CRP) forms extended fibrilar structures that encapsulate liposomes in the presence of Ca(2+). We have observed structures consistent in...

background: we studied the effects of high protein (hp) and balanced diets (bds) on lipid profiles, and high‑sensitive c‑reactive protein (hs‑crp) levels in obese and overweight women. methods: in a parallel designed randomized controlled clinical trial, 60 healthy women with body mass index ≥25 kg/m2, aged 20–46 years, enrolled in an 8‑week investigation at aerobic clubs. they were categorized...

background: c-reactive protein (crp) can be increased after hormonal stimulations. the changes of crp might affect the success of in-vitro fertilization (ivf). objective: the aim of this study was to determine the possible relationship between the serum crp level and outcome of controlled ovarian stimulation, and pregnancy rate in patients undergoing ivf or intra cytoplasmic sperm injection (ic...

introduction: atrial fibrillation (af) is the most prevalent cardiac arrhythmias that cardiologists and internists encounter. the goal of this article is to clarify an overview of the evidence linking inflammation to af existence, which may highlight the effect of some pharmacological agents that have genuine potential to reduce the clinical burden of af by modulating inflammatory pathways. mat...

background objective: to evaluate the utility of specific cut-off values for c- reactive protein (crp) and immature-to-total neutrophil ratio (i/t) as screening tests for meningitis in culture negative early onset sepsis (eos). materials and methods retrospective chart review of 97 newborns with culture negative sepsis who had lumbar puncture performed as part of the sepsis evaluation in a leve...

background: the level of platelet volume (mpv) has been reported to be a laboratory marker in inflammatory cases. objectives: the aim of this study was to seek whether mpv has a role in the diagnosis of acute appendicitis. it was also aimed to show the relationship of mpv with leukocyte count and c-reactive protein (crp) level. materials and methods: this study was conducted via retrospective a...

INTRODUCTION There is growing evidence that inflammation plays a pivotal role in the etiology and progression of atherosclerosis. High C-reactive protein (CRP) levels have been associated with high mortality in patients with acute myocardial infarction (AMI). Furthermore, in animal models CRP has been found to significantly increase infarct size. So there is growing evidence that CRP is not onl...