background and aim: oropharyngeal cancer is a significant cause of death and disability worldwide. in iran it is the 13th and 17th most common cancer found in men and women, respectively. the aim of this study was to investigate etiological factors and clinical features of lesions related to oropharyngeal cancers over a 5-year period in tehran. materials and methods: in this retrospective cross...

The possible association between diabetes and cancer was first launched in 1932, when cancers in the intestine, uterus and pancreas were reported to occur more frequently among patients with diabetes [1]. However, it took some 70 years before the scientific community once more focused on this association. Several observational studies published over the last 10–15 years show unequivocally that ...

A 21-year-old Romanian man presented to our clinic for leanness assessment evolving several years. He had been adopted at the age of 3 years old; hence, no familial history was available. His medical notable dyspraxia, dyslexia, bilateral cryptorchidism, and scoliosis in infancy. practiced water polo, swimming, martial arts, but recent years, amyotrophy weakness both arms developed (Figure, A) ...

The Reproducibility Project: Cancer Biology seeks to address growing concerns about reproducibility in scientific research by conducting replications of 50 papers in the field of cancer biology published between 2010 and 2012. This Registered report describes the proposed replication plan of key experiments from 'Coadministration of a tumor-penetrating peptide enhances the efficacy of cancer dr...

background: besides medical therapy, surgical interventions plays an important role in the treatment of inflammatory bowel disease (ibd), but they also involve complications and advantages. this study was undertaken to determine the characteristics and outcome of surgery in patients with ibd. â  methods: all the files of the patients admitted in nemazee and faghihi hospitals with the final diag...

A 51-year-old man was referred from oncology department with incidental detection of unilateral multiple renal cysts on computed tomography (CT) during evaluation of colon cancer (Figure-1). Abdominal CT revealed enlarged right kidney with variable-sized round, well-marginated multiple cysts without capsule formation or solid content, while the left kidney was normal. Family history was negativ...

background : the main function of the pineal hormone melatonin which is mediated via its two receptors, mtnr1a and mtnr1b, is to mediate dark signals in addition to anti-oxidation, immune system enhancement, protection from radiation, and anti-cancer functions. a common single nucleotide polymorphism in the mtnr1b gene is rs#10830963, which is well known as a risk factor for type 2 diabetes mel...

As suggested by its name, NAFLD is caused by the accumulation of fat in liver cells (Figure 1). Clinically, the abnormal retention of fat in liver cells is termed steatosis. NASH, an advanced form of NAFLD, occurs when the liver becomes inflamed and damaged secondary to fat buildup. The damage caused by NASH is similar to that caused by long-term, heavy alcohol consumption, yet occurs in people...

Background and Objective: The lack of breast cancer screening in young women leads to late disease diagnosis and worse outcomes in this age group. This study was designed to evaluate clinicopathological features and long-term outcomes of young breast cancer women in south of Iran. Materials and Methods: This is a retrospective study of breast cancer patients who were pathologically diagnosed d...

Purpose: To assess the safety and efficacy of the use of concurrent radiation therapy and docetaxel in adjuvant treatment oflocally advanced breast cancer (LABC). Patients and methods: Between February 2009 and January 2013, 62 patients with LABC who underwent primary mastectomy or neoadjuvant chemotherapy (FEC) followed by mastectomy at Assiut University Hospitals were entered into this trial....