= Abstract =The purpose of this study is to evaluate the possibility of application of SRCA to previously frozen tumor tissue. Mouse sarcoma-180 and human squamous cell carcinoma of the uterine cervix were used as implanting tumor specimens. The fresh tumor specimens were frozen by rapid freezing method and stored in a liquid nitrogen tank. On the 7th day of freezing, the specimens were thawed ...

A study of 318 patients with tubal infertility and a control group of 200 unselected infertile women yielded 14 (4.4%) and 1 (0.5%), respectively, with precancerous lesions of the cervix uteri. The one patient in the control group with severe dysplasia was later shown to have tubal infertility. The overall incidence of premalignant lesions of the cervix uteri as reported to the National Cancer ...

A 46-year-old woman presented with lower abdominal pain, diarrhea and irregular vaginal bleeding persisting for the past 2 months. She had a history of cervical cancer treated with concurrent chemoradiotherapy 6 years previously, which was successful. Magnetic resonance imaging with T2-weighted and diffusion images showed a high intensity area in the cervix, suggestive of recurrent cervical can...

  Abstract   Background: Screening is a necessity for country health systems. In undeveloped   countries that have no screening programs, cervical carcinoma is one of the   major causes of mortality and morbidity. Although cervical cancer is preventable   it is poorly controlled in some countries. The main cause of it is unawareness of   people from cervical cancer and screening methods.   Meth...

INTRODUCTION Most studies point at the main role of humanpapilloma virus (HPV) in the development of dysplasia and cervical cancer. Due to the low specificity and sensitivity of morphological diagnostic methods it is necessary to find an adequate marker which would be introduced in the screening program for cervical cancer. Most research suggests that p16INK4a is a specific and sensitive marker...

The aim of this study was to explore the correlation of ezrin and galectin-3 expressions with prognosis in cervical cancer. The immunohistochemical method was applied to detect ezrin and galectin-3 expressions in normal cervix tissues (n=30), cervicitis tissues (n=28), cervical intraepithelial neoplasia (CIN) tissues (classified as I-III, n=89), and cervical carcinoma tissues (n=84). Follow-up ...

There are several differences between neuroendocrine and other types of cervical cancer, in prognosis, diagnosis and treatment. Neuroendocrine cancer of the uterine cervix is a rare and aggressive disease. Small cell carcinoma is classified as a neuroendocrine tumor in the currently used World Health Organization histological classification of tumors of the uterine cervix (2003). Small-cell car...

Chemoradiation is the current standard of care in patients with locally advanced carcinoma cervix. Although extensive literature is available on the acute morbidity due to chemoradiotherapy in women with cancer cervix, most of the studies have been done at carefully prepared academic centers in developed countries (Rose et al., 1999; Maduro et al., 2003; Ikushima et al., 2006; Mahantshetty et a...

Cervical cancer remains a significant health problem. New strategies based on the molecular aspects of cervical carcinogenesis are needed. Chemoprevention represents a novel strategy for cervical cancer prevention. Our group plans phase I and II trials using alpha-difluoromethylornithine, a suicide inhibitor of ornithine decarboxylase and potent antiproliferative chemopreventive agent. We condu...

Given the extended survival of patients diagnosed with cervical cancer, a large number of women are treated with radiotherapy. A second primary cancer has currently become one of the most important radiation-induced injuries as the number of cancer patients who are cured is increasing by virtue of recent advancements in therapeutic radiology. A 56-year-old woman developed two pelvic malignancie...